关键词: Blastomyces gilchristii Minnesota United States blastomycosis fungi respiratory infections whole-genome sequencing

Mesh : Blastomyces / genetics Blastomycosis / epidemiology Humans Minnesota / epidemiology Molecular Epidemiology

来  源:   DOI:10.3201/eid2809.220392

Abstract:
We characterized 2 clusters of blastomycosis cases in Minnesota, USA, using whole-genome sequencing and single-nucleotide polymorphism analyses. Blastomyces gilchristii was confirmed as the cause of infection. Genomic analyses corresponded with epidemiologic findings for cases of B. gilchristii infections, demonstrating the utility of genomic methods for future blastomycosis outbreak investigations.
摘要:
我们对明尼苏达州的2群芽生菌病病例进行了表征,美国,使用全基因组测序和单核苷酸多态性分析。gilchristii芽胞菌被确认为感染的原因。基因组分析与B.gilchristii感染病例的流行病学发现相对应,证明基因组方法在未来芽生菌病爆发调查中的实用性。
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