了解 DNA 修复和细胞色素 p - 450 基因多态性在伴随放化疗的宫颈癌患者中的作用。
关键词: CYP1A1 CYP2E1 DNA repair gene cervical cancer polymorphisms treatment outcome CYP1A1 CYP2E1 DNA repair gene cervical cancer polymorphisms treatment outcome
Mesh : Case-Control Studies Chemoradiotherapy Cisplatin / therapeutic use Cytochrome P-450 CYP1A1 / genetics Cytochrome P-450 CYP2E1 / genetics Cytochrome P-450 Enzyme System / genetics DNA Repair DNA-Binding Proteins / genetics Female Genetic Predisposition to Disease Genotype Humans Polymorphism, Single Nucleotide Uterine Cervical Neoplasms / drug therapy radiotherapy X-ray Repair Cross Complementing Protein 1 / genetics Case-Control Studies Chemoradiotherapy Cisplatin / therapeutic use Cytochrome P-450 CYP1A1 / genetics therapeutic use Cytochrome P-450 CYP2E1 / genetics DNA Repair / genetics DNA-Binding Proteins / genetics Female Genetic Predisposition to Disease Genotype Humans Polymorphism, Single Nucleotide / genetics Uterine Cervical Neoplasms / drug therapy therapy X-ray Repair Cross Complementing Protein 1 / genetics
来 源:
DOI:10.3389/bjbs.2021.10120
PDF(Pubmed)