Abstract：
This study aimed to determine the features and differentiation of Giant Cell Reparative Granuloma (GCRG) and Giant Cell Tumor (GCT) of the head on CT and MRI.
This retrospective study included six patients with histopathology-confirmed head GCRG and 5 patients with histopathology-confirmed head GCT. All images were independently reviewed by two radiologists. The growth pattern, bone changes, MRI signal intensity, enhancement patterns and other image features were recorded. All patients received CT scans and MR images.
All the lesions were located centrally in the bone. Osteolytic bone destruction and expansive growth patterns were observed on CT images. Four of six cases broke the cortical bone with residual cortical bone, and the last two showed a thin cortex in GCRG. Five cases broke the cortical bone with residual cortical bone in GCT. There were enhancing septations in GCT lesions on contrast- enhanced T1-Weighted Images (T1WI) while enhancing septations were not present in GCRG cases. The size of GCT lesions was larger than that of GRCG. GCRG and GCT showed iso-low signals on T1WI and iso-high signals on T2-Weighted Images (T2WI). There was a case with cystic or necrotic lesions in each of the two types of lesions. Osteolytic bone destruction and expansive growth patterns were observed in GCTs and GCRGs.
The size of the GRCG lesion was smaller than that of the GCT. The presence of enhancing septations and the size of the lesion may distinguish GCTs from GCRG.
This retrospective study included six patients with histopathology-confirmed head GCRG and 5 patients with histopathology-confirmed head GCT. All images were independently reviewed by two radiologists. The growth pattern, bone changes, MRI signal intensity, enhancement patterns and other image features were recorded. All patients received CT scans and MR images.
All the lesions were located centrally in the bone. Osteolytic bone destruction and expansive growth patterns were observed on CT images. Four of six cases broke the cortical bone with residual cortical bone, and the last two showed a thin cortex in GCRG. Five cases broke the cortical bone with residual cortical bone in GCT. There were enhancing septations in GCT lesions on contrast- enhanced T1-Weighted Images (T1WI) while enhancing septations were not present in GCRG cases. The size of GCT lesions was larger than that of GRCG. GCRG and GCT showed iso-low signals on T1WI and iso-high signals on T2-Weighted Images (T2WI). There was a case with cystic or necrotic lesions in each of the two types of lesions. Osteolytic bone destruction and expansive growth patterns were observed in GCTs and GCRGs.
The size of the GRCG lesion was smaller than that of the GCT. The presence of enhancing septations and the size of the lesion may distinguish GCTs from GCRG.
摘要：
背景：本研究旨在确定头部巨细胞修复性肉芽肿（GCRG）和巨细胞瘤（GCT）在CT和MRI上的特征和分化。
方法：这项回顾性研究包括6例经组织病理学证实的头部GCRG患者和5例经组织病理学证实的头部GCT患者。所有图像均由两名放射科医师独立检查。增长模式，骨骼变化,MRI信号强度,记录增强模式和其他图像特征。所有患者均接受CT扫描和MR图像。
结果：所有病变均位于骨中央。在CT图像上观察到溶骨性骨破坏和膨胀性生长模式。6例中有4例皮质骨骨折，皮质骨残留，最后两个显示GCRG的皮质薄。GCT中5例皮质骨骨折并残留皮质骨。在对比增强的T1加权图像（T1WI）上，GCT病变中存在增强的分隔，而在GCRG病例中不存在增强的分隔。GCT病灶大小大于GRCG。GCRG和GCT在T1WI上显示等低信号，在T2加权图像（T2WI）上显示等高信号。在这两种类型的病变中，均有一例囊性或坏死性病变。在GCT和GCRGs中观察到溶骨性骨破坏和扩张性生长模式。
结论：GRCG病灶的大小小于GCT。增强隔膜的存在和病变的大小可以将GCT与GCRG区分开。
方法：这项回顾性研究包括6例经组织病理学证实的头部GCRG患者和5例经组织病理学证实的头部GCT患者。所有图像均由两名放射科医师独立检查。增长模式，骨骼变化,MRI信号强度,记录增强模式和其他图像特征。所有患者均接受CT扫描和MR图像。
结果：所有病变均位于骨中央。在CT图像上观察到溶骨性骨破坏和膨胀性生长模式。6例中有4例皮质骨骨折，皮质骨残留，最后两个显示GCRG的皮质薄。GCT中5例皮质骨骨折并残留皮质骨。在对比增强的T1加权图像（T1WI）上，GCT病变中存在增强的分隔，而在GCRG病例中不存在增强的分隔。GCT病灶大小大于GRCG。GCRG和GCT在T1WI上显示等低信号，在T2加权图像（T2WI）上显示等高信号。在这两种类型的病变中，均有一例囊性或坏死性病变。在GCT和GCRGs中观察到溶骨性骨破坏和扩张性生长模式。
结论：GRCG病灶的大小小于GCT。增强隔膜的存在和病变的大小可以将GCT与GCRG区分开。
