关键词: Frontal fibrosing alopecia Lichen planus pigmentosus Nail lichen planus

来  源:   DOI:10.1159/000521715   PDF(Pubmed)

Abstract:
UNASSIGNED: Frontal fibrosing alopecia (FFA) is characterized by irreversible, symmetrical band-like hair loss in the frontotemporal region. Lichen planus pigmentosus (LPP) is a variant of lichen planus (LP) that presents with hyperpigmented macules and patches predominantly in sun-exposed areas. Nail LP is a subtype of LP that can be present alone or with other forms of LP.
UNASSIGNED: We report a rare case of a 59-year-old woman presenting with symmetrical, gray-brown, hyperpigmented lesions on her neck and face, band-like alopecia in the frontotemporal region, severe onycholysis in two fingernails, and prominent longitudinal ridging in all fingernails. Clinical, dermoscopic, and histological findings established a diagnosis of FFA associated with LPP and nail LP was established.
UNASSIGNED: In recent years, it has been established that FFA can be associated with LPP and it is thought to be a variant of lichen planopilaris. Nail involvement is rarely reported in FFA or LPP. To our knowledge, the presence of the three conditions in the same patient has not been previously reported. Although rare we would like to emphasize the importance of a careful examination of the nails in patients with FFA and/or LPP to prevent irreversible nail changes.
摘要:
额叶纤维化脱发(FFA)的特征是不可逆的,额颞区对称的带状脱发。色素性扁平苔藓(LPP)是扁平苔藓(LP)的一种变体,主要在暴露于阳光的区域表现出色素沉着的黄斑和斑块。指甲LP是LP的亚型,可以单独存在或与其他形式的LP一起存在。
我们报告了一例罕见的59岁女性,灰棕色,她的颈部和面部色素沉着过度,额颞区的带状脱发,严重的指甲溶解在两个手指甲,所有指甲都有突出的纵向起皱。临床,皮肤镜,和组织学发现建立了与LPP和指甲LP相关的FFA的诊断。
近年来,已经确定FFA可以与LPP相关,并且被认为是扁平苔藓的变体。在FFA或LPP中很少报道指甲受累。据我们所知,以前没有报道同一患者中存在这三种情况。虽然罕见,我们想强调仔细检查FFA和/或LPP患者的指甲以防止不可逆的指甲变化的重要性。
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