PDF(Pubmed)
Abstract：
Vertebral tuberculosis (TB) is a common form of extrapulmonary TB. Here, the slow-growing Mycobacterium bacillus reaches the disc space through the hematogenous route and leads to various complications. Radiological imaging and histopathology have been the mainstay of diagnosis, but radionuclide imaging techniques using radiolabeled antitubercular drugs have rarely found space in the clinical domain. Here, we present a case of vertebral TB, where a technetium-labeled antitubercular drug, ethambutol, was synthesized and used for imaging the bacteria in vivo. Thus, we demonstrate a rarely used potentially specific agent for tuberculous-infection imaging, which can be produced in-house, and provides rapid results.
摘要：
椎体结核(TB)是肺外结核的常见形式。这里,缓慢生长的分枝杆菌通过血源性途径到达椎间盘间隙，并导致各种并发症。放射影像学和组织病理学一直是诊断的主要手段，但是使用放射性标记的抗结核药物的放射性核素成像技术在临床领域很少发现空间。这里,我们提出了一个椎骨结核的病例，那里是一种有tech标记的抗结核药物，乙胺丁醇,合成并用于体内细菌成像。因此，我们展示了一种很少使用的用于结核感染成像的潜在特异性药物，可以在内部生产，并提供快速的结果。
