Abstract：
The microbial composition of the human vagina differs from that of all other mammals, likely as a consequence of the unique composition of vaginal constituents that promote the selective maintenance and proliferation of distinct bacterial species. Similarly, variations between individual healthy women in genetic, environmental, and medical variables also modify the vaginal lumen composition. The direction and magnitude of immune reactions to microorganisms present in the vagina, responses to stress and non-infectious stimuli, coupled with medical and pregnancy history and environmental exposures, can greatly differ between women. Adaptations to both internal and external pressures will determine the ability of select resident vaginal bacteria to numerically dominate and, therefore, the definition of a \"normal\" vaginal microbiota will substantially differ between individual healthy women.
摘要：
人类阴道的微生物组成不同于所有其他哺乳动物,可能是由于阴道成分的独特组成促进不同细菌物种的选择性维持和增殖。同样，个体健康女性之间的遗传差异，环境,和医学变量也改变了阴道腔的组成。对阴道中存在的微生物的免疫反应的方向和程度，对压力和非感染性刺激的反应，再加上医疗和妊娠史以及环境暴露，女性之间可以有很大的不同。适应内部和外部压力将决定选择常驻阴道细菌在数字上占主导地位的能力，因此,“正常”阴道微生物群的定义在个体健康女性之间会有很大差异。
