PDF(Pubmed)
Abstract：
BACKGROUND: Extramedullary hematopoiesis rarely occurs within the liver alone, and is easily misdiagnosed. The radiological literature on this disease is exclusively case reports. There is a paucity of literature on the role of magnetic resonance imaging (MRI). The most common imaging modalities used are computed tomography and ultrasound. This report aims to provide more data on the appearance of extramedullary hematopoiesis using MRI to help radiologists establish the diagnosis.
METHODS: Three patients (one male and two females) were incidentally found to have a hepatic mass or nodule, without hepatomegaly or splenomegaly. Laboratory tests including liver function, serum hepatic tumor markers, and hepatitis serologic markers were normal. On MRI scans, all lesions showed lower signal intensity on in-phase images than on out-phase images. One case showed changes in signal intensity on T2 weighted images (WI) and diffusion WI, which shifted from hyperintensity to hypointensity with size enlargement between two rounds of imaging examination. These lesions exhibited different enhancement patterns on dynamic contrast enhancement series.
CONCLUSIONS: The MRI signal change and in-/out-phase image might provide useful information and help radiologists establish the diagnosis of intrahepatic extramedullary hematopoiesis.
METHODS: Three patients (one male and two females) were incidentally found to have a hepatic mass or nodule, without hepatomegaly or splenomegaly. Laboratory tests including liver function, serum hepatic tumor markers, and hepatitis serologic markers were normal. On MRI scans, all lesions showed lower signal intensity on in-phase images than on out-phase images. One case showed changes in signal intensity on T2 weighted images (WI) and diffusion WI, which shifted from hyperintensity to hypointensity with size enlargement between two rounds of imaging examination. These lesions exhibited different enhancement patterns on dynamic contrast enhancement series.
CONCLUSIONS: The MRI signal change and in-/out-phase image might provide useful information and help radiologists establish the diagnosis of intrahepatic extramedullary hematopoiesis.
摘要：
背景：髓外造血很少发生在肝脏内，很容易被误诊.关于这种疾病的放射学文献仅是病例报告。关于磁共振成像（MRI）的作用的文献很少。使用的最常见的成像方式是计算机断层扫描和超声。本报告旨在使用MRI提供有关髓外造血外观的更多数据，以帮助放射科医生建立诊断。
方法：三名患者（一名男性和两名女性）偶然发现肝肿块或结节，没有肝肿大或脾肿大。实验室检查包括肝功能，血清肝肿瘤标志物，肝炎血清学标志物正常。在核磁共振扫描中,所有病变在同相图像上的信号强度均低于异相图像.一例在T2加权图像（WI）和扩散WI上显示信号强度的变化，在两轮成像检查之间，随着尺寸的扩大，从高强度转变为低强度。这些病变在动态对比增强系列中表现出不同的增强模式。
结论：MRI信号变化和同相/异相图像可能提供有用的信息，并帮助放射科医生建立肝内髓外造血的诊断。
方法：三名患者（一名男性和两名女性）偶然发现肝肿块或结节，没有肝肿大或脾肿大。实验室检查包括肝功能，血清肝肿瘤标志物，肝炎血清学标志物正常。在核磁共振扫描中,所有病变在同相图像上的信号强度均低于异相图像.一例在T2加权图像（WI）和扩散WI上显示信号强度的变化，在两轮成像检查之间，随着尺寸的扩大，从高强度转变为低强度。这些病变在动态对比增强系列中表现出不同的增强模式。
结论：MRI信号变化和同相/异相图像可能提供有用的信息，并帮助放射科医生建立肝内髓外造血的诊断。
