Abstract：
BACKGROUND: Hematology analyzers provide quick and accurate results in most situations. However, spurious results related to the parameters from the complete blood count (CBC) may be observed in several instances. False increases in WBC count can occur for many reasons, including erythroblasts, insufficiently lysed red blood cells (RBC), platelet aggregates, lipids, and cryoglobulins. However, cases of pseudoleukocytopenia due to plasma related factors are rare.
RESULTS: Here, we report a case of pseudoleukocytopenia in CBC test. It was identified by the peripheral blood smears and different scatter plots of WNR and WDF channel. The interference from plasma was con-firmed by simulating the state of blood in the WBC channel and plasma exchange.
CONCLUSIONS: It was confirmed that the interference of pseudoleukocytopenia was from the plasma. This may be due to the high amount of albumin and other therapeutic drug reactions. Observation of peripheral blood smears and scatter plots can identify this interference.
RESULTS: Here, we report a case of pseudoleukocytopenia in CBC test. It was identified by the peripheral blood smears and different scatter plots of WNR and WDF channel. The interference from plasma was con-firmed by simulating the state of blood in the WBC channel and plasma exchange.
CONCLUSIONS: It was confirmed that the interference of pseudoleukocytopenia was from the plasma. This may be due to the high amount of albumin and other therapeutic drug reactions. Observation of peripheral blood smears and scatter plots can identify this interference.
摘要：
背景：血液分析仪在大多数情况下都能提供快速准确的结果。然而,在几种情况下，可能会观察到与全血细胞计数（CBC）参数相关的虚假结果。WBC计数的错误增加可能有很多原因，包括成红细胞,红细胞（RBC）裂解不足，血小板聚集体,脂质，和冷球蛋白.然而,由于血浆相关因素引起的假性白细胞减少病例很少见。
结果：这里，我们在CBC试验中报告一例假性白细胞减少症。通过外周血涂片和WNR和WDF通道的不同散点图进行鉴定。通过模拟WBC通道中的血液状态和血浆交换来确定血浆的干扰。
结论：证实了假性红细胞减少症的干扰来自血浆。这可能是由于大量的白蛋白和其他治疗药物反应。观察外周血涂片和散点图可以识别这种干扰。
结果：这里，我们在CBC试验中报告一例假性白细胞减少症。通过外周血涂片和WNR和WDF通道的不同散点图进行鉴定。通过模拟WBC通道中的血液状态和血浆交换来确定血浆的干扰。
结论：证实了假性红细胞减少症的干扰来自血浆。这可能是由于大量的白蛋白和其他治疗药物反应。观察外周血涂片和散点图可以识别这种干扰。
