Abstract：
BACKGROUND: Pheochromocytomas are neoplasms originating from neuroectodermal chromaffin cells leading to excess catecholamine production. They are notorious for causing a triad of headaches, palpitations, and sweats. Though the Menard triad is one to be vigilant of, symptomatic presentation can vary immensely, hence the tumor earning the label \"the great masquerader.\"
METHODS: We report a case of pheochromocytoma initially presenting with cortical blindness secondary to posterior reversible encephalopathy syndrome and thrombotic microangiopathy from malignant hypertension. Our patient was seen in our facility less than a week prior to this manifestation and discharged after an unremarkable coronary ischemia work-up. In the outpatient setting, she had been prescribed multiple anti-hypertensives with remarkably elevated blood pressure throughout her hospitalization history.
CONCLUSIONS: Pheochromocytoma presenting with malignant hypertension and hypertensive encephalopathy should be expected if left untreated; nonetheless, the precipitation of cortical blindness is rare in the literature. This case contributes an additional vignette to the growing literature revolving adrenal tumors and their symptomatic presentation along with complex management. It also serves to promote increased diagnostic suspicion among clinicians upon evaluating patients with refractory hypertension.
METHODS: We report a case of pheochromocytoma initially presenting with cortical blindness secondary to posterior reversible encephalopathy syndrome and thrombotic microangiopathy from malignant hypertension. Our patient was seen in our facility less than a week prior to this manifestation and discharged after an unremarkable coronary ischemia work-up. In the outpatient setting, she had been prescribed multiple anti-hypertensives with remarkably elevated blood pressure throughout her hospitalization history.
CONCLUSIONS: Pheochromocytoma presenting with malignant hypertension and hypertensive encephalopathy should be expected if left untreated; nonetheless, the precipitation of cortical blindness is rare in the literature. This case contributes an additional vignette to the growing literature revolving adrenal tumors and their symptomatic presentation along with complex management. It also serves to promote increased diagnostic suspicion among clinicians upon evaluating patients with refractory hypertension.
摘要：
背景：嗜铬细胞瘤是源自神经外胚层嗜铬细胞的肿瘤，导致产生过量的儿茶酚胺。他们因引起头痛而臭名昭著，心悸,出汗。尽管梅纳德三合会是一个值得警惕的人，症状表现可能变化很大，因此，肿瘤获得了“伟大的伪装者”的标签。
方法：我们报告一例嗜铬细胞瘤，最初表现为皮质盲，继发于后部可逆性脑病综合征和恶性高血压血栓性微血管病。在这种表现前不到一周，我们的患者在我们的设施中被发现，并在不明显的冠状动脉缺血检查后出院。在门诊环境中，在她的整个住院历史中,她服用了多种降压药物,血压显著升高.
结论：嗜铬细胞瘤表现为恶性高血压和高血压性脑病，如果不及时治疗，皮质盲的沉淀在文献中很少见。这种情况为越来越多的有关肾上腺肿瘤及其症状表现以及复杂管理的文献提供了额外的插图。在评估难治性高血压患者时，它还可以促进临床医生对诊断的怀疑。
方法：我们报告一例嗜铬细胞瘤，最初表现为皮质盲，继发于后部可逆性脑病综合征和恶性高血压血栓性微血管病。在这种表现前不到一周，我们的患者在我们的设施中被发现，并在不明显的冠状动脉缺血检查后出院。在门诊环境中，在她的整个住院历史中,她服用了多种降压药物,血压显著升高.
结论：嗜铬细胞瘤表现为恶性高血压和高血压性脑病，如果不及时治疗，皮质盲的沉淀在文献中很少见。这种情况为越来越多的有关肾上腺肿瘤及其症状表现以及复杂管理的文献提供了额外的插图。在评估难治性高血压患者时，它还可以促进临床医生对诊断的怀疑。
