Abstract:
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired demyelinating disease of the peripheral nervous system with unknown etiology. Alopecia universalis, an advanced form of alopecia areata (AA), is a condition characterized by complete hair loss. Here we report the first case of childhood CIDP associated with AA who was successfully treated with a combination of intravenous immunoglobulin (IVIg) and corticosteroids. CASE REPORT: This case describes a nine-year-old Japanese girl who developed alopecia, progressive muscle weakness, and eventually loss of walking ability (at ages 2, 4, and 7, respectively). She was treated with IVIg and prednisolone combination therapy, which improved muscle weakness and alopecia. She was positive for serum IgG-GM2 type anti-glycolipid antibodies, which may be associated with this rare combination of diseases.
摘要:
慢性炎症性脱髓鞘性多发性神经病(CIDP)是一种病因不明的外周神经系统获得性脱髓鞘疾病。普遍脱发,斑秃(AA)的一种高级形式,是一种以完全脱发为特征的病症。在这里,我们报告了首例与AA相关的儿童期CIDP,该患者成功使用静脉注射免疫球蛋白(IVIg)和皮质类固醇联合治疗。案例报告:这个案例描述了一个9岁的日本女孩,她患上了脱发,进行性肌肉无力,并最终丧失行走能力(分别在2、4和7岁时)。她接受了IVIg和泼尼松龙联合治疗,改善肌肉无力和脱发。血清IgG-GM2型抗糖脂抗体阳性,这可能与这种罕见的疾病组合有关。