Abstract:
Circulating progesterone concentrations during the growth of the ovulatory follicle and early embryo development have been positively associated with embryo quality and survival and pregnancy success. As a potent luteotropic agent with LH-like activity, human chorionic gonadotropin (hCG) has been tested in different studies to improve pregnancy outcomes by increasing circulating progesterone concentrations during the growth of the ovulatory follicle or early embryonic development. Nevertheless, hCG has produced inconsistent, contradictory, and intriguing results. Furthermore, recent research indicates that hCG, when used before artificial insemination, may affect physiological events necessary for the ovulation of a viable oocyte. In addition, the use of hCG-inducing accessory corpus luteum during the estrous cycle seems to disturb luteolysis and follicle and luteal dynamics during the estrous cycle. This literature review discusses past and current research exploring the effects of hCG on the estrous cycle characteristics and pregnancy per artificial insemination and embryo transfer.
摘要:
排卵卵泡生长和早期胚胎发育过程中的循环孕酮浓度与胚胎质量、存活和妊娠成功呈正相关。作为一种具有LH样活性的强效促黄体化剂,人绒毛膜促性腺激素(hCG)已经在不同的研究中进行了测试,通过在排卵卵泡生长或早期胚胎发育期间增加循环孕酮浓度来改善妊娠结局.然而,HCG产生了不一致的,矛盾的,和有趣的结果。此外,最近的研究表明,hCG,在人工授精前使用时,可能会影响活卵母细胞排卵所必需的生理事件。此外,在发情周期中使用诱导hCG的辅助黄体似乎会干扰发情周期中的黄体溶解以及卵泡和黄体动力学。这篇文献综述讨论了过去和现在的研究,探索了hCG对每次人工授精和胚胎移植的发情周期特征和妊娠的影响。