METHODS: Cohort of children with VLBW born between 2002 and 2017. Association between neonatal somatometry (z-score by Fenton and IW-21) and risk of short stature (<-2 DS), head circumference <-2 DS and malnutrition at 2 years (BMI < -2 DS) was analyzed (WHO charts).
RESULTS: 513 children with a mean gestational age of 30.05 ± 2.5 weeks were included. Birth and discharge weight z-score by Fenton and IW-21 were useful for predicting risk of short stature and malnutrition at 2 years (without differences in the AUC of the ROC curves). Weight z-score at discharge was also useful for predicting head circumference < -2 DS. At 2 years, prevalence of short stature, head circumference < -2 DS, and malnutrition was 17.2, 4.1, and 6.1%, respectively. Low weight for gestational age and length of stay were identified as independent risk factors for short stature at 2 years.
CONCLUSIONS: Discharge weight z-score is useful for predicting risk of short stature, malnutrition and head circumference < -2 DS at 2 years in very low birth weight children, with no statistical difference between using Fenton or IW-21 charts.
方法:2002年至2017年出生的VLBW儿童队列。新生儿躯体测量(Fenton和IW-21的z评分)与身材矮小(<-2DS)的风险之间的关联,分析头围<-2DS和2年营养不良(BMI<-2DS)(WHO图表)。
结果:纳入513名平均胎龄为30.05±2.5周的儿童。Fenton和IW-21的出生和出院体重z评分可用于预测2年时身材矮小和营养不良的风险(ROC曲线的AUC无差异)。出院时的体重z评分也可用于预测头围<-2DS。在2年,身材矮小的患病率,头围<-2DS,营养不良分别为17.2%、4.1%和6.1%,分别。胎龄低体重和住院时间被确定为2年身材矮小的独立危险因素。
结论:出院体重z评分可用于预测身材矮小的风险,极低出生体重儿童在2年时营养不良和头围<-2DS,使用Fenton或IW-21图表之间没有统计学差异。