PDF(Pubmed)
Abstract：
Since the beginning of the novel coronavirus disease-2019 (COVID-19) pandemic, physical medicine and rehabilitation specialists have played an important role in fighting this disease apart from the pulmonary rehabilitation. As a high number of patients have needed immobilization and intensive care unit (ICU) treatment, many complications have emerged inevitably. Heterotopic ossification (HO) is one of these complications. Herein, we present a case of young male patient who had widespread HO in his shoulders, elbows, and hips. Although he managed to survive, he still has difficulty in ambulation and daily living activities. Given the continuing high prevalence of COVID-19, many patients would need immobilization and ICU treatment. Therefore, causes of HO should be scrutinized, physicians and caregivers need to raise vigilance, and comprehensive protective measures should be put in place. On the other hand, as HO is used to be diagnosed quite frequently in the patients with neurological diseases, diagnosis of HO in the COVID-19 patients should not automatically be linked to the stay in the ICU. Yet, it is a fact that impaired immune response is prevalent both in COVID-19 and HO. The correlation between COVID-19 and HO is remarkable, but further research is needed to establish a causal relationship.
摘要：
自2019年新型冠状病毒病(COVID-19)大流行开始以来，除了肺康复外，物理医学和康复专家在抗击这种疾病方面发挥了重要作用。由于大量患者需要固定和重症监护病房（ICU）治疗，许多并发症不可避免地出现了。异位骨化（HO）是这些并发症之一。在这里，我们介绍了一例年轻男性患者，他的肩膀上有广泛的HO，肘部,和臀部。虽然他设法活了下来,他在步行和日常生活活动方面仍然有困难。鉴于COVID-19的持续高患病率，许多患者需要固定和ICU治疗。因此,HO的原因应该仔细检查，医生和护理人员需要提高警惕，并应采取全面的保护措施。另一方面,因为HO在神经系统疾病的患者中经常被诊断出来，在COVID-19患者中，HO的诊断不应自动与在ICU的停留时间相关。然而，事实上，免疫反应受损在COVID-19和HO中都很普遍。COVID-19与HO的相关性显著，但是需要进一步的研究来建立因果关系。
