Abstract：
Diabetes is a major public health concern with a high risk of onset. It can lead to glycometabolism disorders. Improvement in diet is an effective way to regulate metabolic disorders. The fruits of Lycium barbarum, an ancient tonic and a traditional Chinese medicine, have shown beneficial effects against chronic metabolic diseases. Lycium barbarum polysaccharides, polyphenols, carotenoids and amino acids are the major natural bioactive compounds in the fruits of Lycium barbarum. They have many physiological activities and medicinal value and have shown significant anti-diabetic effects. This article reviews the effective actions of the main bioactive compounds in Lycium barbarum fruits in reducing blood glucose, intestinal and renal inflammation, retinal damage and other complications, discusses the possible metabolism of these bioactive compounds in the pathogenesis of diabetes, and explains the basic mechanism of regulation of blood glucose. Although the current research is limited to animal experiments and in vitro cell experiments, we have provided reliable evidence for our reports based on previous studies. Lycium barbarum fruits is a beneficial food that can interfere with carbohydrate metabolism in vivo, a significant direction for the development of Lycium barbarum, and can be used as a potential target for treating diabetes.
摘要：
糖尿病是一个主要的公共卫生问题，发病风险很高。它可以导致糖代谢紊乱。改善饮食是调节代谢紊乱的有效途径。枸杞的果实，一种古老的滋补品和传统的中药，已显示出对慢性代谢性疾病的有益作用。枸杞多糖，多酚，类胡萝卜素和氨基酸是枸杞果实中主要的天然生物活性化合物。它们具有许多生理活性和药用价值，并显示出显著的抗糖尿病作用。本文综述了枸杞果实中主要生物活性化合物在降血糖方面的作用。肠道和肾脏炎症，视网膜损伤和其他并发症，讨论了这些生物活性化合物在糖尿病发病机理中的可能代谢，并解释了血糖调节的基本机制。虽然目前的研究仅限于动物实验和体外细胞实验,我们根据以往的研究为我们的报告提供了可靠的证据.枸杞果实是一种有益的食物，可以干扰体内碳水化合物的代谢，枸杞的重要发展方向，可作为治疗糖尿病的潜在靶点。
