PDF(Pubmed)
Abstract：
UNASSIGNED: Coinfection with Pneumocystis jirovecii and Mycobacterium tuberculosis is rare in HIV-seronegative patients. Because it is associated with unknown morbidity and a high mortality rate especially in patients with immunosuppression, health care practitioners should have a high index of suspicion when dealing with such patients.
UNASSIGNED: A 66-year-old man with glucocorticoid therapy for 9 years had a fever after getting a cold and developed respiratory failure rapidly within 3 days. He was given trimethoprim-sulfamethoxazole empirically before Pneumocystis pneumonia (PCP) was confirmed with the presence of cysts in the sputum. Although there was a partial improvement of symptoms, an area of consolidation on the left upper lung lobe gradually enlarged. Bronchoscopy was performed 3 times and Mycobacterium tuberculosis infection was finally diagnosed. For 1 years, he was treated with standard antituberculosis agents, and his psychological well-being was managed using traditional Chinese medicine techniques. After 3 years of follow-up, his outcome was very good.
UNASSIGNED: HIV-seronegative patients on long-term glucocorticoid therapy in areas with a high incidence of Mycobacterium tuberculosis may be co-infected with Pneumocystis jirovecii. When opportunistic infections are suspected, diagnostic procedures including invasive ones should be performed as soon as possible and appropriate interventions need to be carried out promptly.
UNASSIGNED: A 66-year-old man with glucocorticoid therapy for 9 years had a fever after getting a cold and developed respiratory failure rapidly within 3 days. He was given trimethoprim-sulfamethoxazole empirically before Pneumocystis pneumonia (PCP) was confirmed with the presence of cysts in the sputum. Although there was a partial improvement of symptoms, an area of consolidation on the left upper lung lobe gradually enlarged. Bronchoscopy was performed 3 times and Mycobacterium tuberculosis infection was finally diagnosed. For 1 years, he was treated with standard antituberculosis agents, and his psychological well-being was managed using traditional Chinese medicine techniques. After 3 years of follow-up, his outcome was very good.
UNASSIGNED: HIV-seronegative patients on long-term glucocorticoid therapy in areas with a high incidence of Mycobacterium tuberculosis may be co-infected with Pneumocystis jirovecii. When opportunistic infections are suspected, diagnostic procedures including invasive ones should be performed as soon as possible and appropriate interventions need to be carried out promptly.
摘要：
■在HIV血清阴性患者中，与吉罗韦西肺孢子虫和结核分枝杆菌合并感染很少见。因为它与未知的发病率和高死亡率相关，特别是在免疫抑制患者中，医护人员在与此类患者打交道时，应该有很高的怀疑指数。
■一名66岁男子接受糖皮质激素治疗9年，感冒后发烧，并在3天内迅速发展为呼吸衰竭。在确认痰中存在囊肿之前，先根据经验给予甲氧苄啶-磺胺甲恶唑。虽然症状有部分改善,左上肺叶实变区逐渐增大。进行3次支气管镜检查，最终诊断为结核分枝杆菌感染。1年来,他接受了标准的抗结核药物治疗,他的心理健康是用中医技术管理的。经过3年的随访，他的结果非常好。
■在结核分枝杆菌高发地区接受长期糖皮质激素治疗的HIV血清阴性患者可能与肺孢子虫合并感染。当怀疑机会性感染时，包括侵入性诊断程序在内的诊断程序应尽快进行，并且需要及时进行适当的干预措施。
■一名66岁男子接受糖皮质激素治疗9年，感冒后发烧，并在3天内迅速发展为呼吸衰竭。在确认痰中存在囊肿之前，先根据经验给予甲氧苄啶-磺胺甲恶唑。虽然症状有部分改善,左上肺叶实变区逐渐增大。进行3次支气管镜检查，最终诊断为结核分枝杆菌感染。1年来,他接受了标准的抗结核药物治疗,他的心理健康是用中医技术管理的。经过3年的随访，他的结果非常好。
■在结核分枝杆菌高发地区接受长期糖皮质激素治疗的HIV血清阴性患者可能与肺孢子虫合并感染。当怀疑机会性感染时，包括侵入性诊断程序在内的诊断程序应尽快进行，并且需要及时进行适当的干预措施。
