PDF(Pubmed)
Abstract：
Severe fever with thrombocytopenia syndrome (SFTS) is a zoonotic disease with a high mortality rate for humans and cats. The clinical course and prognosis of SFTS in dogs remains unclear. In the present study, we investigated the clinical and epidemiological characteristics of SFTS virus (SFTSV) infection in dogs. All evaluated dogs exhibited an acute course and symptoms including fever (57.1%), anorexia (57.1%), depression (42.9%), and vomiting (35.7%). Thrombocytopenia was present in 45.5% of dogs, while jaundice was not observed. C-reactive protein, alanine transaminase, and alkaline phosphatase were elevated in some cases. Viral clearance occurred within 6 to 26 days. Phylogenetic analysis revealed that the SFTSV sequences were consistent with viruses circulating in the Republic of Korea. As dogs often live in close contact with humans, awareness of the clinical and epidemiological features of SFTS in dogs is crucial. Further large-scale studies are necessary to investigate SFTSV infection in dogs.
摘要：
严重发热伴血小板减少综合征（SFTS）是一种人畜共患疾病，对人和猫的死亡率很高。犬SFTS的临床病程和预后尚不清楚。在本研究中,我们调查了犬SFTS病毒（SFTSV）感染的临床和流行病学特征。所有被评估的狗都表现出急性病程和症状，包括发烧（57.1％）。厌食症(57.1%),抑郁症(42.9%)，和呕吐(35.7%)。45.5%的狗存在血小板减少症，而未观察到黄疸。C反应蛋白,丙氨酸转氨酶，碱性磷酸酶在某些情况下升高。病毒清除发生在6至26天内。系统发育分析表明，SFTSV序列与大韩民国流行的病毒一致。由于狗经常与人类密切接触，了解狗SFTS的临床和流行病学特征至关重要。需要进一步的大规模研究来研究狗的SFTSV感染。
