Abstract：
This updated and upgraded S2k guideline deals with the diagnosis and treatment of rosacea, which is a common, chronic inflammatory skin disease mostly affecting the face. Initially, rosacea is characterized by recurrent erythema, telangiectasia and flushing. Later, the inflammatory component predominates, with persistent erythema with follicular papules, papulopustules and pustules. The development of phyma, which usually occurs on the acral localizations, is the most severe manifestation. For the treatment of rosacea, the interdisciplinary guideline committee, with representatives of the German Dermatological Society (DDG), the Professional Association of German Dermatologists (BVDD), the German Opthalmological Society (DOG), the Society for Dermopharmacy (GD), the Swiss Society for Dermatology and Venereology (SGDV) and the German Rosacea Aid e. V., recommends the avoidance of trigger factors and topical applications of metronidazole, azelaic acid or ivermectin. For symptomatic treatment of persistent centrofacial erythema, the topical vasoconstrictors brimonidine or oxymetazoline can also be used. Systemic therapy is recommended for therapy-resistant and severe forms of rosacea papulopustulosa. The drug of choice is low-dose doxycycline. Alternatively, low-dose isotretinoin can be recommended. Ocular rosacea should be treated with lid margin hygiene. For topical treatment, ciclosporin eye drops, azithromycin, ivermectin or metronidazole are suggested.
摘要：
这个更新和升级的S2k指南涉及酒渣鼻的诊断和治疗，这是一个常见的，慢性炎症性皮肤病主要影响面部。最初，酒渣鼻的特征是复发性红斑，毛细血管扩张和潮红。稍后，炎症成分占主导地位，持续性红斑伴毛囊丘疹，丘疹脓疱和脓疱。phyma的发展，通常发生在肢端位置，是最严重的表现。对于酒渣鼻的治疗，跨学科指导委员会，与德国皮肤病学会（DDG）的代表，德国皮肤科医师专业协会（BVDD），德国光学学会（DOG），皮肤病学会(GD)，瑞士皮肤病和性病学会（SGDV）和德国酒渣鼻援助e.V.,建议避免触发因素和局部应用甲硝唑，壬二酸或伊维菌素。对于持续性面部中心红斑的对症治疗，局部血管收缩剂溴莫尼定或羟甲唑啉也可以使用。系统治疗推荐用于治疗抗性和严重形式的酒渣鼻。选择的药物是低剂量多西环素。或者，可推荐低剂量异维A酸。眼部酒渣鼻应进行眼睑边缘卫生治疗。对于局部治疗，环孢素滴眼液,阿奇霉素,建议使用伊维菌素或甲硝唑。
