Mesh : Cervical Vertebrae / diagnostic imaging pathology surgery Giant Cell Tumor of Tendon Sheath / diagnostic imaging pathology surgery Humans Laminectomy Magnetic Resonance Imaging Synovial Membrane / pathology

来  源:   DOI:10.1038/s41394-022-00538-2

Abstract:
Tenosynovial giant cell tumours (TSGCTs) usually arise from the synovial membranes of tendon sheaths, bursa, and joints. They are rarely found in the spine. Lesions of the upper cervical spine (C1/2) are extremely rare, with only 13 previous cases reported in the literature. Of these, all previous anterior upper cervical cases (C1/2) have been deemed unresectable and have been managed with immunotherapy or radiological surveillance.
We report two cases of TSGCST in the cervical spine: one with a lesion at C1/2 and another at C6/7.
The location of our C1/2 lesion was unique, allowing for a new endoscopic endonasal tissue biopsy method and a new transoral surgical approach for successful gross total resection. Our C6/7 lesion had a more typical location and was removed via a C6/7 laminectomy.
摘要:
肌腱滑膜巨细胞瘤(TSGCT)通常来自肌腱鞘的滑膜。Bursa,和关节。很少在脊柱中发现。上颈椎(C1/2)的病变极为罕见,文献中仅报道了13例以前的病例。其中,以前所有的上颈前路病例(C1/2)均被认为是不可切除的,并接受了免疫治疗或放射学监测.
我们报告了两例颈椎TSGCST:一个在C1/2处病变,另一个在C6/7处病变。
我们的C1/2病变的位置是独特的,允许一种新的内镜鼻内组织活检方法和一种新的经口手术方法,以成功进行全切除。我们的C6/7病变具有更典型的位置,并通过C6/7椎板切除术切除。
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