关键词: Desmoid tumor Desmoid-type fibromatosis Fine needle aspiration Intra-abdominal Pancreas Desmoid tumor Desmoid-type fibromatosis Fine needle aspiration Intra-abdominal Pancreas

来  源:   DOI:10.1016/j.anndiagpath.2022.152015

Abstract:
Desmoid-type fibromatosis (desmoid tumors) which involve the pancreas is an infrequent diagnosis which clinically can mimic both neoplastic and non-neoplastic lesions of the pancreas. The cytologic features of loosely cohesive cytologically bland (myo)fibroblastic cells are non-specific, however the long fascicular growth pattern and the presence of β-catenin mutation with positive nuclear immunohistochemical staining or molecular testing allows for definitive diagnosis. While many previously reported desmoid tumors of the pancreas have been surgically resected, conservative management with a \"watch and wait\" approach is also an effective mode of management for these tumors. Herein, we report the largest case series of pancreatic desmoid tumors with clinical, cytopathologic, and radiologic correlation.
摘要:
涉及胰腺的纤维瘤病(纤维瘤)是一种罕见的诊断,在临床上可以模拟胰腺的肿瘤性和非肿瘤性病变。松散内聚的细胞学上枯燥的(myo)成纤维细胞的细胞学特征是非特异性的,然而,长束状生长模式和β-catenin突变的存在以及核免疫组织化学染色或分子检测阳性,可以明确诊断.虽然许多先前报道的胰腺纤维状肿瘤已经通过手术切除,“观察和等待”的保守治疗方法也是治疗这些肿瘤的有效模式。在这里,我们报道了胰腺硬纤维瘤的最大病例系列,细胞病理学,和放射学相关性。
公众号