PDF(Pubmed)
Abstract：
UNASSIGNED: Central apnea (CA) events always can be seen in the polysomnographic (PSG) reports of children with obstructive sleep apnea (OSA), and sometimes the central apnea index (CAI) is higher than the obstructive apnea and hypopnea index (OAHI). Commonly, the clinicians only attribute it to the age. This study aims to elucidate the distribution characteristics and major factors associated with CA in pediatric OSA.
UNASSIGNED: A retrospective chart review of PSG data of children with OSA from January 2017 to March 2018 was performed.
UNASSIGNED: 856 children (317 girls and 539 boys, 4.9 ± 2.4 years) were involved. 50.1% (429/856) had a CAI > 1, and 2.9% (25/856) had a CAI >5. Children with a CAI >1 had a higher OAHI, arousal index (AI), oxygen desaturation index (ODI), and a longer REM period, but a younger age and a shorter slow-wave sleep (SWS) phase. Multivariate binary logistic regression showed that with a 1% increased REM period, the risk of the CAI being >1 increased by 5.3% (p < 0.001). The CAI increased with an increasing OAHI (p = 0.003). The possibility of a CAI ≤ 1 increased with age (p < 0.001), and boys were more likely to have a CAI ≤ 1 (p = 0.001).
UNASSIGNED: In addition to obstructive apnea (OA), almost all children with OSA also had CA, and a CAI > 1 was most likely to occur. The OAHI and REM period were risk factors for an increased CAI, and age and male sex were protective factors.
UNASSIGNED: A retrospective chart review of PSG data of children with OSA from January 2017 to March 2018 was performed.
UNASSIGNED: 856 children (317 girls and 539 boys, 4.9 ± 2.4 years) were involved. 50.1% (429/856) had a CAI > 1, and 2.9% (25/856) had a CAI >5. Children with a CAI >1 had a higher OAHI, arousal index (AI), oxygen desaturation index (ODI), and a longer REM period, but a younger age and a shorter slow-wave sleep (SWS) phase. Multivariate binary logistic regression showed that with a 1% increased REM period, the risk of the CAI being >1 increased by 5.3% (p < 0.001). The CAI increased with an increasing OAHI (p = 0.003). The possibility of a CAI ≤ 1 increased with age (p < 0.001), and boys were more likely to have a CAI ≤ 1 (p = 0.001).
UNASSIGNED: In addition to obstructive apnea (OA), almost all children with OSA also had CA, and a CAI > 1 was most likely to occur. The OAHI and REM period were risk factors for an increased CAI, and age and male sex were protective factors.
摘要：
■在阻塞性睡眠呼吸暂停（OSA）儿童的多导睡眠图（PSG）报告中总是可以看到中枢呼吸暂停（CA）事件，有时中枢呼吸暂停指数（CAI）高于阻塞性呼吸暂停和低通气指数（OAHI）。通常,临床医生只把它归因于年龄。本研究旨在阐明儿童OSA中与CA相关的分布特征和主要因素。
■对2017年1月至2018年3月OSA患儿的PSG数据进行回顾性图表回顾。
■856名儿童（317名女孩和539名男孩，涉及4.9±2.4年）。50.1%(429/856)的CAI>1,2.9%(25/856)的CAI>5。CAI>1的儿童有更高的OAHI，唤醒指数（AI），氧饱和度指数(ODI),和较长的REM期，但年龄较小，慢波睡眠（SWS）阶段较短。多元二元logistic回归显示，REM期增加1%，CAI>1的风险增加了5.3%(p<0.001)。CAI随着OAHI的增加而增加(p=0.003)。CAI≤1的可能性随着年龄的增长而增加（p<0.001），男孩更可能有CAI≤1（p=0.001）。
■除了阻塞性呼吸暂停（OA），几乎所有患有OSA的儿童也有CA，并且CAI>1是最有可能发生的。OAHI和REM期是CAI增加的危险因素，年龄和男性是保护因素。
■对2017年1月至2018年3月OSA患儿的PSG数据进行回顾性图表回顾。
■856名儿童（317名女孩和539名男孩，涉及4.9±2.4年）。50.1%(429/856)的CAI>1,2.9%(25/856)的CAI>5。CAI>1的儿童有更高的OAHI，唤醒指数（AI），氧饱和度指数(ODI),和较长的REM期，但年龄较小，慢波睡眠（SWS）阶段较短。多元二元logistic回归显示，REM期增加1%，CAI>1的风险增加了5.3%(p<0.001)。CAI随着OAHI的增加而增加(p=0.003)。CAI≤1的可能性随着年龄的增长而增加（p<0.001），男孩更可能有CAI≤1（p=0.001）。
■除了阻塞性呼吸暂停（OA），几乎所有患有OSA的儿童也有CA，并且CAI>1是最有可能发生的。OAHI和REM期是CAI增加的危险因素，年龄和男性是保护因素。
