Abstract：
Although interest in aesthetic medicine is growing, the focus is often placed outside of the facial area, namely on the skin of the neck and cleavage. Exposure to the sun and muscle movements cause the prompt development of wrinkles that may appear there, even before they show up on the face. We conducted a literature review devoted to micro-needling to identify its role in anti-ageing treatments and to determine the gaps in current knowledge. A search in Medline identified 52 publications for neck and face micro-needling. Micro-needling is an anti-ageing procedure that involves making micro-punctures in the skin to induce skin remodelling by stimulating the fibroblasts responsible for collagen and elastin production. It can be applied to the skin of the face, neck, and cleavage. Two to four weeks should be allowed between repeated procedures to achieve an optimal effect. The increase in collagen and elastin in the skin can reach 400% after 6 months, with an increase in the thickness of the stratum granulosum occurring for up to 1 year. In conclusion, micro-needling can be considered an effective and safe aesthetic medicine procedure which is conducted at low costs due to its low invasiveness, low number of adverse reactions, and short recovery time. Little evidence identified in the literature suggests that this procedure requires further research.
摘要：
尽管人们对美容医学的兴趣正在增长，焦点通常放在面部区域之外，即在颈部和乳沟的皮肤上。暴露在阳光下和肌肉运动会导致可能出现的皱纹迅速发展，甚至在他们出现在脸上之前。我们进行了有关微针刺的文献综述，以确定其在抗衰老治疗中的作用，并确定当前知识的差距。在Medline中进行的搜索确定了52种有关颈部和面部微针刺的出版物。微针刺是一种抗衰老程序，涉及在皮肤中进行微穿刺，通过刺激负责胶原蛋白和弹性蛋白产生的成纤维细胞来诱导皮肤重塑。它可以应用于面部皮肤，脖子,和乳沟。重复程序之间应允许两到四周以达到最佳效果。6个月后，皮肤中胶原蛋白和弹性蛋白的增加可以达到400%，随着颗粒层厚度的增加发生长达1年。总之,微针刺可以被认为是一种有效和安全的美容医学程序，由于其低侵入性而以低成本进行，不良反应数量少，恢复时间短。文献中很少有证据表明该程序需要进一步研究。
