Abstract：
Müller-Weiss Disease (MWD) is a rare foot disease with unclear etiology but frequently occurred in women. Due to the resistance to conservative treatment, surgical therapy has gradually occupied a necessary position in the clinical management of MWD. Joint fusion surgery is a commonly used treatment for MWD, which could effectively alleviate pain, correct deformation, and restore function. A total of 12 MWD patients (III-V stage) were enrolled in this study. All patients showed no significant improvement in conservative treatment and further received the triple and talonavicular arthrodesis. All patients were followed up with an average follow-up of 16.8 ± 1.19 months (mean ± SD). The triple and talonavicular arthrodesis significantly ameliorated the pain and walking dysfunction in the affected foot. The American Orthopedic Foot Andankle Society (AOFAS) scores dramatically increased from 43.4 ± 16.1 to 85.3 ± 6.2. Meanwhile, the conducting of triple and talonavicular arthrodesis improved the X-ray length (15.5 ± 0.8 vs. 14.3 ± 0.9 cm) and arch height (18.6 ± 0.9 vs. 10.2 ± 0.7 mm) and reduced the Meary-Tomeno angle (1.3 ± 2.5 vs. 2.14 ± 4.8°). The triple and talonavicular arthrodesis achieved a satisfying therapeutic effect on MWD patients at the III-V stage, which improved patients\' outcomes and the quality of life.
摘要：
Müller-Weiss病（MWD）是一种罕见的足部疾病，病因不明，但常见于女性。由于对保守治疗的抵抗力，外科治疗逐渐在MWD的临床管理中占据了必要的地位。关节融合术是治疗MWD的常用方法,可以有效缓解疼痛，正确的变形，和恢复功能。本研究共纳入12名MWD患者(III-V期)。所有患者在保守治疗中没有显着改善，并进一步接受了三联和距骨关节固定术。所有患者均获随访,平均随访16.8±1.19个月(平均值±SD)。三联和距骨关节固定术可显着改善患足的疼痛和步行功能障碍。美国矫形外科足踝协会（AOFAS）的得分从43.4±16.1急剧增加到85.3±6.2。同时,进行三重和距骨关节固定术可改善X射线长度（15.5±0.8vs.14.3±0.9cm）和足弓高度（18.6±0.9vs.10.2±0.7mm），并减小了Meary-Tomeno角度（1.3±2.5与2.14±4.8°)。三联和距骨关节固定术对III-V期MWD患者取得了满意的治疗效果，这改善了患者的预后和生活质量。
