关键词: MRI NSGCT cancer imaging seminoma testicular tumor ultrasound MRI NSGCT cancer imaging seminoma testicular tumor ultrasound MRI NSGCT cancer imaging seminoma testicular tumor ultrasound

来  源:   DOI:10.3390/cancers14153594

Abstract:
BACKGROUND: The purpose of this study was to retrospectively analyze the diagnostic accuracy of magnetic resonance imaging (MRI) examinations of the scrotum in comparison with standard ultrasound (US) and histopathology.
METHODS: A retrospective multi-center analysis of MRI examinations of the scrotum performed between 06/2008 and 04/2021 was conducted.
RESULTS: A total of n = 113 patients were included. A total of 53 histopathologies were available, with 52.8% malignant and 50.9% benign findings. Related to histopathology, imaging was true negative, false negative, false positive, and true positive in 4.1%, 2.1%, 25.0% and 37.5% for standard ultrasound (US) and 9.1%, 1.8%, 25.5% and 43.6% for MRI. Sensitivity, specificity, positive predictive value and negative predictive value were 94.7%, 20.0%, 36.0% and 88.9% for US and 85.7%, 72.8%, 52.1% and 93.7% for MRI, respectively. Benign lesions were significantly smaller than malignant ones in standard US (p = 0.001), histopathology (p = 0.001) and MRI (p = 0.004). The size of malignant tumors did not differ significantly between histopathology and standard US (0.72) and between histopathology and MRI (p = 0.88).
CONCLUSIONS: MRI shows good sensitivity and specificity for the estimation of testicular tumors in this collective. Benign lesions are significantly smaller than malignant ones. Both MRI and US can estimate the size of malignant tumors adequately.
摘要:
背景:本研究的目的是回顾性分析与标准超声(US)和组织病理学比较的阴囊磁共振成像(MRI)检查的诊断准确性。
方法:对2008年6月至2021年4月进行的阴囊MRI检查进行回顾性多中心分析。
结果:共纳入113例患者。共有53种组织病理学,有52.8%的恶性和50.9%的良性结果。与组织病理学有关,影像学检查为真阴性,假阴性,假阳性,4.1%为真阳性,2.1%,标准超声(美国)为25.0%和37.5%,为9.1%,1.8%,MRI为25.5%和43.6%。灵敏度,特异性,阳性预测值和阴性预测值分别为94.7%,20.0%,美国的36.0%和88.9%,85.7%,72.8%,MRI为52.1%和93.7%,分别。标准US中良性病变明显小于恶性病变(p=0.001),组织病理学(p=0.001)和MRI(p=0.004)。恶性肿瘤的大小在组织病理学和标准US(0.72)之间以及在组织病理学和MRI之间没有显着差异(p=0.88)。
结论:MRI显示了该集合中睾丸肿瘤评估的良好敏感性和特异性。良性病变明显小于恶性病变。MRI和US都可以充分估计恶性肿瘤的大小。
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