Abstract：
Background: Coronavirus disease (COVID-19) hospitalization has been related to Post-Traumatic Stress Disorder (PTSD). Available information is limited by insufficient follow-up and lack of longitudinal studies. Baseline factors (e.g., sex; obesity) have been related to PTSD, but post-hospitalization factors have not been studied. Objective: This study aimed to analyse prevalence, baseline, post-discharge factors and possible clinical courses of PTSD after hospitalization for COVID-19. Method: 109 patients (94.7% of the original sample) completed a programme of three follow-up telephone assessments during the year following hospitalization. Data included clinical and sociodemographic factors as well as psychometric tools assessing PTSD, social support, and perception of threat to life (PTL). Mixture model analysis was performed to study the longitudinal course of PTSD symptoms. Chronic (>6 months) PTSD predictors were also analysed. Results: 1-year PTSD period prevalence was 23.9%, peaking at six months; 11% of the patients suffered chronic PTSD. Pre- and post-hospitalization factors influenced the onset and course of PTSD over time. These included working status, PTL, and lack of social support. Interestingly, obesity, pulmonary diseases and family cluster infection seem specifically related to PTSD following COVID-19. Inversely, clinical interventions, older age and male gender were protective. Conclusions: PTSD following COVID-19 hospitalization is common. The analysed demographic, social, clinical, and psychological factors predict PTSD symptomatology over time and can modify odds of a chronic course. Clinicians could better identify cases at risk of a chronic PTSD course. Finally, treatment as usual appeared related to a better outcome and should be proposed to patients with PTSD.
摘要：
背景：冠状病毒病（COVID-19）住院与创伤后应激障碍（PTSD）有关。现有信息受到随访不足和缺乏纵向研究的限制。基线因素(例如，性；肥胖)与创伤后应激障碍有关，但住院后因素尚未研究。目的：本研究旨在分析患病率，基线,COVID-19住院后PTSD的出院后因素和可能的临床病程。方法：109例患者（占原始样本的94.7％）在住院后的一年内完成了一项由三个随访电话评估的计划。数据包括临床和社会人口统计学因素以及评估PTSD的心理测量工具，社会支持,和对生命威胁的感知（PTL）。进行混合模型分析以研究PTSD症状的纵向过程。还分析了慢性（>6个月）PTSD预测因子。结果:1年PTSD患病率为23.9%,6个月时达到峰值；11%的患者患有慢性PTSD。住院前后因素影响PTSD的发病和病程。这些包括工作状态，PTL,缺乏社会支持。有趣的是,肥胖，肺部疾病和家族聚集性感染似乎与COVID-19后的PTSD特别相关。相反，临床干预措施，年龄较大和男性性别是保护性的。结论：COVID-19住院后PTSD很常见。分析的人口统计，社会,临床,随着时间的推移，心理因素可以预测PTSD症状，并可以改变慢性病程的几率。临床医生可以更好地识别有慢性PTSD病程风险的病例。最后,照常治疗似乎与更好的结果相关，应建议PTSD患者使用。
