Abstract:
The literature evaluating the effect of prehabilitation programmes on postoperative outcomes and quality of life of patients with gynaecological cancer undergoing surgery was reviewed. Databases including Pubmed, Medline, EMBASE (Ovid) and PsycINFO were systematically searched to identify studies evaluating the effect of prehabilitation programmes on patients with gynaecological cancer. Both unimodal and multimodal prehabilitation programmes were included encompassing physical exercise and nutritional and psychological support. Primary outcomes were surgical complications and quality of life. Secondary outcomes were anthropometric changes and adherence to the prehabilitation programme. Seven studies fulfilled the inclusion criteria, comprising 580 patients. Included studies were nonrandomised prospective studies (n = 4), retrospective studies (n = 2) and one case report. Unimodal programmes and multimodal programmes were included. In patients with ovarian cancer, multimodal prehabilitation resulted in significantly reduced hospital stay and time to chemotherapy. In patients with endometrial and cervical cancer, prehabilitation was associated with significant weight loss, but had no significant effects on surgical complications or mortality. No adverse events of the programmes were reported. Evidence on the effect of prehabilitation for patients with gynaecological cancer is limited. Future studies are needed to determine the effects on postoperative complications and quality of life.
摘要:
回顾了评估康复计划对妇科癌症手术患者术后结局和生活质量影响的文献。包括Pubmed、Medline,系统搜索EMBASE(Ovid)和PsycINFO,以确定评估康复计划对妇科癌症患者影响的研究。包括单一模式和多模式康复前方案,包括体育锻炼以及营养和心理支持。主要结果是手术并发症和生活质量。次要结果是人体测量变化和对康复计划的依从性。七项研究符合纳入标准,580名患者。纳入的研究是非随机前瞻性研究(n=4),回顾性研究(n=2)和1例报告。包括了单一模式方案和多模式方案。在卵巢癌患者中,多模式康复可显著减少住院时间和化疗时间.在子宫内膜癌和宫颈癌患者中,康复与显著的体重减轻有关,但对手术并发症或死亡率无显著影响.没有报告方案的不良事件。关于妇科癌症患者康复效果的证据有限。需要进一步的研究来确定对术后并发症和生活质量的影响。