PDF(Pubmed)
Abstract：
A 34-year-old male was referred to our hospital for a possible pancreatic mass detected by computed tomography (CT) that was performed to find the cause of acute pancreatitis. Multiple imaging tests, including contrast-enhanced CT scan, magnetic resonance imaging, contrast-enhanced endoscopic ultrasonography, and endoscopic retrograde pancreatography, revealed a solid mass occupying the head of the main pancreatic duct (MDP), and pancreaticoduodenectomy was performed. In the resected specimen, the tumor showed expansive growth from the pancreatic parenchyma to the MDP and formed a tumor plug. Histopathological findings together with immunostaining findings led to the diagnosis of pancreatic acinar cell carcinoma (PACC). The patient was alive and recurrence-free for 11 years after surgery. Extension into the MDP is more common in PACC than in conventional pancreatic ductal adenocarcinoma. PACC patients with MDP extension may have less aggressive clinicopathologic characteristics, and a relatively good prognosis can be expected.
摘要：
一名34岁的男性因计算机断层扫描（CT）检测到的胰腺肿块而被转诊到我们医院，以寻找急性胰腺炎的原因。多次成像测试,包括增强CT扫描,磁共振成像，超声造影增强内镜,和内镜逆行胰管造影术,发现一个固体肿块占据了主胰管（MDP）的头部，并进行胰十二指肠切除术。在切除的标本中，肿瘤显示从胰腺实质到MDP的扩张性生长，并形成肿瘤栓。组织病理学发现以及免疫染色发现导致胰腺腺泡细胞癌（PACC）的诊断。患者在手术后11年内存活且无复发。与常规胰腺导管腺癌相比，PACC中MDP的延伸更常见。MDP扩张的PACC患者可能具有较少侵袭性的临床病理特征，并且可以预期相对良好的预后。
