Abstract：
Cryoglobulinemia encompasses a group of diseases with circulating aberrant Igs, which can cause systemic cryoglobulinemic vasculitis, including cryoglobulinemic glomerulonephritis. The complexities of different types and changing etiologies of cryoglobulinemias determine its heterogeneous clinical manifestations and diagnostic difficulties. In this issue of Kidney International, Javaugue et al. have emphasized the diagnostic points of cryoglobulinemic glomerulonephritis and hematological disorders as the major culprits of noninfectious cryoglobulinemic glomerulonephritis in a large cohort.
摘要：
冷球蛋白血症包括一组循环异常Ig的疾病，会导致全身冷球蛋白血症性血管炎，包括冷球蛋白血症性肾小球肾炎。冷球蛋白血症的不同类型和病因学的复杂性决定了其临床表现和诊断困难的异质性。在本期国际肾脏杂志上，Javaugueetal.强调了冷球蛋白血症性肾小球肾炎的诊断要点和血液系统疾病是大型队列中非感染性冷球蛋白血症性肾小球肾炎的主要罪魁祸首。
