Abstract：
UNASSIGNED: Aging and chronic heart failure (CHF) are responsible for the temporal inhomogeneity of electrocardiogram (ECG) repolarization phase. In the past, short period repolarization-dispersion parameters were used as makers of mortality risk in different heart diseases, yet. Aim of this work was to evaluate risk of mortality or worsening condition in CHF elderly subjects by mean of these repo-larization variables.
UNASSIGNED: An observational, prospective cohort study was performed, collecting 5 minutes ECG recordings to assess the mean and standard deviation (SD) of the following variables: QT end (QTe), QT peak (QTp) and T peak to T end (Te) in 117 decompensated CHF (age range: from 49 to 103 years). 30-day mortality and high levels of NT-pro BNP (<75 percentile) were considered markers of decompensated CHF.
UNASSIGNED: A total of 27 patients (23%) died during the 30-day follow-up (overall mortality rate 23%). Te mean (odd ratio (OR): 1.04, 95% confidence limit (Cl 7u): 1.02-1.09, p<0.01), NT-pro BNP (OR: 1.00, 95% cl: 1.00-1.00, p<0.01) and LVMI (OR : 0.98, 95% cl: 0.96-0.10, p<0.05) were associated to risk of mortality at the multivariable logistic analysis. On the contrary, the same statistical analysis selected TeSD (OR: 1.36, 95% cl: 1.16-1.59, p<0.001) and LVEF (OR: 0.91, 95% cl: 0.87-0.95, p<0.001) as marker of decompensated CHF.
UNASSIGNED: In decompensated CHF elderly subjects, Te mean seem be associated to mortality and TeSD could be considered a risk factor for CHF worsening and complications. These evidences could provide useful tools for telemonitoring CHF elderly patients, amelio-rating treatments and outcomes.
UNASSIGNED: An observational, prospective cohort study was performed, collecting 5 minutes ECG recordings to assess the mean and standard deviation (SD) of the following variables: QT end (QTe), QT peak (QTp) and T peak to T end (Te) in 117 decompensated CHF (age range: from 49 to 103 years). 30-day mortality and high levels of NT-pro BNP (<75 percentile) were considered markers of decompensated CHF.
UNASSIGNED: A total of 27 patients (23%) died during the 30-day follow-up (overall mortality rate 23%). Te mean (odd ratio (OR): 1.04, 95% confidence limit (Cl 7u): 1.02-1.09, p<0.01), NT-pro BNP (OR: 1.00, 95% cl: 1.00-1.00, p<0.01) and LVMI (OR : 0.98, 95% cl: 0.96-0.10, p<0.05) were associated to risk of mortality at the multivariable logistic analysis. On the contrary, the same statistical analysis selected TeSD (OR: 1.36, 95% cl: 1.16-1.59, p<0.001) and LVEF (OR: 0.91, 95% cl: 0.87-0.95, p<0.001) as marker of decompensated CHF.
UNASSIGNED: In decompensated CHF elderly subjects, Te mean seem be associated to mortality and TeSD could be considered a risk factor for CHF worsening and complications. These evidences could provide useful tools for telemonitoring CHF elderly patients, amelio-rating treatments and outcomes.
摘要：
■衰老和慢性心力衰竭（CHF）是心电图（ECG）复极化阶段的时间不均匀性的原因。在过去,短期复极化-弥散参数被用作不同心脏病死亡风险的指标，yet.这项工作的目的是通过这些回购变量来评估CHF老年受试者的死亡或病情恶化的风险。
■观测，进行前瞻性队列研究，收集5分钟的ECG记录，以评估以下变量的平均值和标准偏差（SD）：QT结束（QTe），117例失代偿CHF的QT峰（QTp）和T峰至T端（Te）（年龄范围：49至103岁）。30天死亡率和高水平的NT-proBNP(<75百分位数)被认为是失代偿CHF的标志物。
■在30天的随访中，共有27名患者（23％）死亡（总死亡率23％）。Te平均值（奇数比（OR）：1.04，95％置信限（Cl7u）：1.02-1.09，p<0.01），在多变量逻辑分析中,NT-proBNP(OR:1.00,95%cl:1.00-1.00,p<0.01)和LVMI(OR:0.98,95%cl:0.96-0.10,p<0.05)与死亡风险相关。相反,相同的统计学分析选择TeSD(OR:1.36,95%cl:1.16-1.59,p<0.001)和LVEF(OR:0.91,95%cl:0.87-0.95,p<0.001)作为失代偿CHF的标志物。
■在失代偿CHF老年受试者中，平均似乎与死亡率有关，TeSD可被认为是CHF恶化和并发症的危险因素。这些证据可以为CHF老年患者的远程监测提供有用的工具，改善治疗和结果。
■观测，进行前瞻性队列研究，收集5分钟的ECG记录，以评估以下变量的平均值和标准偏差（SD）：QT结束（QTe），117例失代偿CHF的QT峰（QTp）和T峰至T端（Te）（年龄范围：49至103岁）。30天死亡率和高水平的NT-proBNP(<75百分位数)被认为是失代偿CHF的标志物。
■在30天的随访中，共有27名患者（23％）死亡（总死亡率23％）。Te平均值（奇数比（OR）：1.04，95％置信限（Cl7u）：1.02-1.09，p<0.01），在多变量逻辑分析中,NT-proBNP(OR:1.00,95%cl:1.00-1.00,p<0.01)和LVMI(OR:0.98,95%cl:0.96-0.10,p<0.05)与死亡风险相关。相反,相同的统计学分析选择TeSD(OR:1.36,95%cl:1.16-1.59,p<0.001)和LVEF(OR:0.91,95%cl:0.87-0.95,p<0.001)作为失代偿CHF的标志物。
■在失代偿CHF老年受试者中，平均似乎与死亡率有关，TeSD可被认为是CHF恶化和并发症的危险因素。这些证据可以为CHF老年患者的远程监测提供有用的工具，改善治疗和结果。
