关键词: Bone metastasis Case report Neuroendocrine tumors Review

Mesh : Adult Bone Neoplasms / secondary Humans Liver Neoplasms / diagnosis pathology secondary Male Neuroendocrine Tumors / diagnosis pathology Osteosclerosis Pain

来  源:   DOI:10.1111/os.13384

Abstract:
BACKGROUND: The neuroendocrine tumor (NET) is rare, accounting for about 0.5% of all tumors. NETs have the characteristics of metastasis, especially lymph nodes, liver, spleen, and bone.
METHODS: We report a 30-year-old man diagnosed with a NET with bone metastasis and presented with waist and leg pain. The imaging findings of this case showed multiple osteosclerosis and no apparent bone destruction. We collected the patient\'s previous examinations, including laboratory, imaging, and pathological examination to get a precise diagnosis. Given this case, we carried out symptomatic support treatment to relieve the patients\' pain symptoms.
CONCLUSIONS: Bone metastases from NETs of unknown primary site are rare in both clinical and imaging manifestations. The disease is mainly manifested as multiple osteosclerosis, accompanied by muscle soreness and pain. It is recommended to try chemotherapy for this disorder.
摘要:
背景:神经内分泌肿瘤(NET)很少见,约占所有肿瘤的0.5%。NET具有转移的特点,尤其是淋巴结,肝脏,脾,脾还有骨头.
方法:我们报告了一名30岁的男性,被诊断患有骨转移,并表现为腰腿痛。该病例的影像学表现为多发性骨硬化,无明显的骨破坏。我们收集了病人以前的检查,包括实验室,成像,和病理检查以获得准确的诊断。鉴于这种情况,我们进行了对症支持治疗,以缓解患者的疼痛症状。
结论:原发部位未知的NETs骨转移在临床和影像学表现上都是罕见的。本病主要表现为多发性骨硬化,伴有肌肉酸痛和疼痛。建议尝试化疗治疗这种疾病。
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