PDF(Pubmed)
Abstract：
In visceral leishmaniasis (as in all leishmanial infections), microscopic diagnosis is made by observing the intracellular amastigote form, complete with a kinetoplast, in aspirate smears or biopsied tissue. In the 2 clinically-ill patients described here, intracellular inclusions were demonstrated in a bone marrow aspirate or a colon tissue biopsy. Kinetoplasts associated with the inclusions were not identified in the marrow aspirate smear (although the patient was treated for visceral leishmaniasis), but were identified retrospectively in the colonic tissue (although the patient was treated for histoplasmosis). Both cases illustrate the importance to clinical consultants of microscopically observing (or not) an associated kinetoplast when faced with a tissue aspirate or biopsy specimen showing intracellular inclusions.
摘要：
在内脏利什曼病（如所有利什曼病感染）中，显微镜诊断是通过观察细胞内的amastigote形式，完整的动体，在抽吸涂片或活检组织中。在这里描述的2名临床病人中，在骨髓穿刺液或结肠组织活检中证实了细胞内包涵体。骨髓穿刺涂片中未发现与包涵体相关的叶绿体（尽管患者接受了内脏利什曼病治疗），但在结肠组织中回顾性发现（尽管患者接受了组织胞浆菌病治疗）。两种情况都表明，当面对组织抽吸物或活检标本显示细胞内包涵体时，显微镜观察（或不观察）相关动体对临床顾问的重要性。
