Primary Effusion Lymphoma Presenting As Parapneumonic Pleural Effusion.

原发性积液淋巴瘤表现为肺炎旁胸腔积液。

• 发表时间: Jul 2022
• 来源期刊: Cureus
• DOI: 10.7759/cureus.26794
• PMID: 35847166
• 文章类型: Case Reports
• 作者列表: Gujarathi R,Candula N,Chippa V,Kadakia M,Alkhasawneh A,Gujarathi R,Candula N,Chippa V,Kadakia M,Alkhasawneh A

关键词: hhv-8; hiv aids antiretrovial therapy; immunocompromised patient; non hodgkin's lymphoma; rare cause of pleural effusion; hhv-8; hiv aids antiretrovial therapy; immunocompromised patient; non hodgkin's lymphoma; rare cause of pleural effusion

Abstract

Primary effusion lymphoma (PEL) is a rare form of high-grade non-Hodgkin\'s lymphoma that usually occurs in patients with compromised immunity or human immunodeficiency virus (HIV) infection. PEL is a B-cell lymphoma that principally presents as effusions without a tumor mass. We present a case of a 56-year-old African-American male with a medical history of HIV admitted to the hospital with right lung lower lobe pneumonia and parapneumonic effusion. Thoracentesis and pleural fluid cytology led to the diagnosis of PEL. He received treatment with chemotherapy and antiretroviral therapy (ART). The emphasis is to investigate immunocompromised patients presenting with pleural effusion for PEL, as it is a rare ailment with a high mortality rate.

摘要

原发性积液性淋巴瘤（PEL）是一种罕见的高级别非霍奇金淋巴瘤，通常发生在免疫力低下或人类免疫缺陷病毒（HIV）感染的患者中。PEL是一种B细胞淋巴瘤，主要表现为无肿瘤肿块的积液。我们介绍了一例56岁的非裔美国男性，有HIV病史，因右肺下叶肺炎和肺炎旁积液入院。胸腔穿刺术和胸膜液细胞学检查导致PEL的诊断。他接受了化疗和抗逆转录病毒治疗（ART）。重点是调查出现PEL胸腔积液的免疫功能低下患者，因为这是一种罕见的疾病，死亡率很高。