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Abstract：
A malignant germ cell tumor (GCT) might contain or transform into malignant non-germ cell histology, commonly referred to as somatic-type malignancy (SM). It is a rare phenomenon with poorly understood pathogenesis. SMs are mostly associated with teratomas and are mainly observed in late relapsing cases. There are no consensus guidelines on the management of SMs; however, surgery is considered to be the mainstay of treatment. Prognosis is variable depending on the time of diagnosis, site of relapse, and type of histology. Here, we present a case of a 44-year-old male with a history of mixed GCT stage IIA, initially managed with right radical orchiectomy, who developed a relapse of GCT 10 years later with an SM of adenocarcinoma subtype.
摘要：
恶性生殖细胞肿瘤（GCT）可能包含或转化为恶性非生殖细胞组织学，通常称为躯体型恶性肿瘤（SM）。这是一种罕见的现象，对其发病机理知之甚少。SM主要与畸胎瘤相关，主要在晚期复发病例中观察到。没有关于SM管理的共识准则；然而，手术被认为是治疗的主要手段。预后取决于诊断时间，复发部位，和组织学类型。这里,我们介绍了一个44岁的男性，有混合GCT阶段IIA的历史，最初采用右根治性睾丸切除术，10年后发展为GCT复发，SM为腺癌亚型。
