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Abstract：
Integrative traditional Korean medicine (TKM) treatment including herbal medicine and acupuncture has been used frequently by parents in South Korea for the treatment of children with idiopathic short stature (ISS). We aimed to report the TKM treatments currently being used for children with ISS and explore their therapeutic effects. The medical records of children who met the criteria for ISS and who had been treated with TKM for the management of ISS were retrospectively reviewed. In total, 116 patients (mean [standard deviation] age, 8.07 [3.08] years; 52.6% girls) enrolled in the study. Their mean height percentile was 1.45 and body mass index was 16.19 kg/m2. During the study period of 5 years, participants visited the outpatient clinic an average of 2.93 times; the mean number of days to the next visit was 101 days. All patients received herbal medicine treatment, and the formulation was mainly decoction type. Additional treatments including ear acupuncture and moxibustion were also used. After treatment with TKM, the height percentile and standard deviation scores increased in both girls and boys (P < .001 and P < .01, respectively). Additionally, the predicted adult height, estimated based on bone age, increased in girls (P < .05). This study provided preliminary data for future research in TKM use in children with ISS.
摘要：
在韩国，父母经常使用包括草药和针灸在内的韩国传统医学（TKM）治疗来治疗特发性身材矮小（ISS）的儿童。我们旨在报告目前用于ISS儿童的TKM治疗方法，并探讨其治疗效果。回顾性审查了符合ISS标准并接受TKM治疗以管理ISS的儿童的病历。总的来说,116名患者(平均[标准差]年龄，8.07[3.08]年；52.6％的女孩）参加了研究。他们的平均身高百分位数为1.45，体重指数为16.19kg/m2。在5年的研究期间，参与者平均到门诊就诊2.93次;下一次就诊的平均天数为101天.所有患者均接受中药治疗,剂型以汤剂为主。还使用了其他治疗方法，包括耳针和艾灸。用TKM治疗后，女孩和男孩的身高百分位数和标准差得分均增加（分别为P<.001和P<.01）。此外,预测的成人身高,根据骨龄估计，女孩增加（P<0.05）。这项研究为未来在ISS儿童中使用TKM的研究提供了初步数据。
