PDF(Pubmed)
Abstract：
UNASSIGNED: Anxiety disorders are highly prevalent and cause significant distress, disability, and cost. Medication adverse effects and interactions increase in mid-life and late-life, highlighting the need for effective non-pharmacological interventions.
UNASSIGNED: We aimed to evaluate the extent of evidence supporting exercise interventions for anxiety and subthreshold anxiety disorders in mid-life and late-life.
UNASSIGNED: Systematic review.
UNASSIGNED: We searched MEDLINE, PsycINFO, Embase, Emcare, Ovid Nursing, CINAHL Plus, Cochrane Library, Health Collection, Humanities & Social Sciences Collection, and https://clinicaltrials.gov databases for trials published January 1994-May 2019. Randomised controlled trials of exercise interventions involving aerobic exercise or resistance training for adults aged 40 years and above with anxiety or subthreshold anxiety disorders in residential or health settings were identified. The primary outcome was change in anxiety. We excluded trials including participants aged below 40 years, participants with diagnosis of separation anxiety, selective mutism, obsessive-compulsive disorder, acute stress disorder and post-traumatic stress disorder, and head-to-head comparisons of interventions. Trial quality was assessed using the Cochrane Risk of Bias Tool and evidence synthesised in narrative form.
UNASSIGNED: Four trials totalling 132 participants met inclusion criteria, although some had methodological limitations. Interventions included a home-based resistance training intervention, supervised group-based aerobic intervention, Tai Chi intervention, and supervised group-based aerobic and strength intervention. Three trials included late-life participants and the fourth mid-life. Three trials demonstrated greater reductions in anxiety in the intervention group compared with control. The fourth trial showed pre-post reductions in anxiety in both groups, with between-group difference not reaching statistical significance.
UNASSIGNED: There is limited supportive evidence suggesting that exercise interventions have potential to be effective, feasible and safe non-pharmacological interventions for anxiety and subthreshold anxiety disorders in mid-life and late-life. The heterogeneity, limited number and high risk of bias of some trials meant that we were not able to conduct a meta-analysis. Tailoring of interventions may improve uptake and reduce dropout. The paucity of research in this area with only four included trials demonstrates the urgent need for future and larger trials to provide proof of concept, data about effective types and doses of exercise interventions, and guidance to community, clinical, and public health services.
UNASSIGNED: We aimed to evaluate the extent of evidence supporting exercise interventions for anxiety and subthreshold anxiety disorders in mid-life and late-life.
UNASSIGNED: Systematic review.
UNASSIGNED: We searched MEDLINE, PsycINFO, Embase, Emcare, Ovid Nursing, CINAHL Plus, Cochrane Library, Health Collection, Humanities & Social Sciences Collection, and https://clinicaltrials.gov databases for trials published January 1994-May 2019. Randomised controlled trials of exercise interventions involving aerobic exercise or resistance training for adults aged 40 years and above with anxiety or subthreshold anxiety disorders in residential or health settings were identified. The primary outcome was change in anxiety. We excluded trials including participants aged below 40 years, participants with diagnosis of separation anxiety, selective mutism, obsessive-compulsive disorder, acute stress disorder and post-traumatic stress disorder, and head-to-head comparisons of interventions. Trial quality was assessed using the Cochrane Risk of Bias Tool and evidence synthesised in narrative form.
UNASSIGNED: Four trials totalling 132 participants met inclusion criteria, although some had methodological limitations. Interventions included a home-based resistance training intervention, supervised group-based aerobic intervention, Tai Chi intervention, and supervised group-based aerobic and strength intervention. Three trials included late-life participants and the fourth mid-life. Three trials demonstrated greater reductions in anxiety in the intervention group compared with control. The fourth trial showed pre-post reductions in anxiety in both groups, with between-group difference not reaching statistical significance.
UNASSIGNED: There is limited supportive evidence suggesting that exercise interventions have potential to be effective, feasible and safe non-pharmacological interventions for anxiety and subthreshold anxiety disorders in mid-life and late-life. The heterogeneity, limited number and high risk of bias of some trials meant that we were not able to conduct a meta-analysis. Tailoring of interventions may improve uptake and reduce dropout. The paucity of research in this area with only four included trials demonstrates the urgent need for future and larger trials to provide proof of concept, data about effective types and doses of exercise interventions, and guidance to community, clinical, and public health services.
摘要：
■焦虑症非常普遍，会导致严重的痛苦，残疾,和成本。药物不良反应和相互作用在中年和晚年增加，强调需要有效的非药物干预措施。
■我们的目的是评估支持在中年和晚年对焦虑症和阈下焦虑症进行运动干预的证据的程度。
■系统评价。
■我们搜索了MEDLINE,PsycINFO,Embase,Emcare,奥维德护理,CINAHLPlus,科克伦图书馆,HealthCollection,人文社会科学集,和https://clinicaltrials.gov数据库，用于1994年1月至2019年5月发布的试验。确定了在居住或健康环境中对40岁及以上患有焦虑症或阈值以下焦虑症的成年人进行有氧运动或阻力训练的运动干预的随机对照试验。主要结果是焦虑的改变。我们排除了包括40岁以下参与者的试验，诊断为分离焦虑的参与者，选择性的mutism,强迫症,急性应激障碍和创伤后应激障碍，和干预措施的头对头比较。使用Cochrane偏差风险工具评估试验质量，并以叙述形式合成证据。
■四项试验共132名参与者符合纳入标准，虽然有些有方法上的局限性。干预措施包括家庭抵抗训练干预，有监督的团体有氧干预，太极干预,以及有监督的基于小组的有氧和力量干预。三项试验包括晚期参与者和第四个中年参与者。三项试验表明，与对照组相比，干预组的焦虑减少更大。第四项试验显示，两组患者的焦虑在术后前均有所减轻，组间差异未达到统计学意义。
■有有限的支持性证据表明运动干预有可能有效，对中年和晚年焦虑和阈下焦虑障碍的可行和安全的非药物干预措施。异质性，一些试验数量有限且偏倚风险较高,这意味着我们无法进行荟萃分析.定制干预措施可以改善吸收并减少辍学。该领域的研究很少，只有四项纳入试验，这表明迫切需要未来更大的试验来提供概念证明。关于运动干预的有效类型和剂量的数据，和对社区的指导，临床,和公共卫生服务。
■我们的目的是评估支持在中年和晚年对焦虑症和阈下焦虑症进行运动干预的证据的程度。
■系统评价。
■我们搜索了MEDLINE,PsycINFO,Embase,Emcare,奥维德护理,CINAHLPlus,科克伦图书馆,HealthCollection,人文社会科学集,和https://clinicaltrials.gov数据库，用于1994年1月至2019年5月发布的试验。确定了在居住或健康环境中对40岁及以上患有焦虑症或阈值以下焦虑症的成年人进行有氧运动或阻力训练的运动干预的随机对照试验。主要结果是焦虑的改变。我们排除了包括40岁以下参与者的试验，诊断为分离焦虑的参与者，选择性的mutism,强迫症,急性应激障碍和创伤后应激障碍，和干预措施的头对头比较。使用Cochrane偏差风险工具评估试验质量，并以叙述形式合成证据。
■四项试验共132名参与者符合纳入标准，虽然有些有方法上的局限性。干预措施包括家庭抵抗训练干预，有监督的团体有氧干预，太极干预,以及有监督的基于小组的有氧和力量干预。三项试验包括晚期参与者和第四个中年参与者。三项试验表明，与对照组相比，干预组的焦虑减少更大。第四项试验显示，两组患者的焦虑在术后前均有所减轻，组间差异未达到统计学意义。
■有有限的支持性证据表明运动干预有可能有效，对中年和晚年焦虑和阈下焦虑障碍的可行和安全的非药物干预措施。异质性，一些试验数量有限且偏倚风险较高,这意味着我们无法进行荟萃分析.定制干预措施可以改善吸收并减少辍学。该领域的研究很少，只有四项纳入试验，这表明迫切需要未来更大的试验来提供概念证明。关于运动干预的有效类型和剂量的数据，和对社区的指导，临床,和公共卫生服务。
