PDF(Pubmed)
Abstract：
Esthesioneuroblastoma is a rare malignancy originating from the olfactory epithelium. Treatment consists of surgical resection with strong consideration for adjuvant treatment in advanced Kadish stage and high Hyams grade. In the modern era, overall outcomes for esthesioneuroblastoma are favorable compared with many other sinonasal malignancies with 5-year overall survival estimated to be 80%. When selecting the optimal surgical approach, the surgeon must consider the approach that will allow for a negative margin resection and adequate reconstruction. In appropriately selected patients, endoscopic outcomes appear at least equivalent to open approaches and unilateral endoscopic approach may be used in select olfactory preservation cases.
摘要：
表皮神经母细胞瘤是一种罕见的起源于嗅觉上皮的恶性肿瘤。治疗包括手术切除，并强烈考虑晚期Kadish期和高Hyams等级的辅助治疗。在现代,与许多其他鼻腔鼻窦恶性肿瘤相比,麻醉神经母细胞瘤的总体结局良好,5年总生存率估计为80%.在选择最佳手术方法时，外科医生必须考虑允许阴性切缘切除和充分重建的方法。在适当选择的患者中，内镜结局至少与开放入路相当,单侧内镜入路可用于部分保留嗅觉的病例.
