Abstract：
BACKGROUND: Chronic wounds are susceptible to colonization with gram-positive and gram-negative bacteria that may be resistant to antimicrobial dressings and systemic antibiotics. In January 2004, the US Food and Drugs Administration approved use of medicinal larvae for use in humans and animals for resistant organisms. Despite use in adults, there is a paucity of evidence evaluating its efficacy and safety in the pediatric population.
METHODS: T was a 5-year-old boy with several chronic wounds infected with multidrug-resistant Pseudomonas aeruginosa. The wounds were originally treated with chemical debridement, dressings containing ionic silver, negative-pressure wound therapy (NPWT), and antibiotics without success. Consequently, a multidisciplinary team implemented maggot debridement therapy (MDT).
CONCLUSIONS: After MDT, one wound completely epithelialized and the other wounds achieved a reduction in size with 70% epithelization. Therapy also led to a reduction in wound odor, exudate, and pain. The other wounds were closed after additional management with dressing containing nanocrystalline silver and NPWT.
METHODS: T was a 5-year-old boy with several chronic wounds infected with multidrug-resistant Pseudomonas aeruginosa. The wounds were originally treated with chemical debridement, dressings containing ionic silver, negative-pressure wound therapy (NPWT), and antibiotics without success. Consequently, a multidisciplinary team implemented maggot debridement therapy (MDT).
CONCLUSIONS: After MDT, one wound completely epithelialized and the other wounds achieved a reduction in size with 70% epithelization. Therapy also led to a reduction in wound odor, exudate, and pain. The other wounds were closed after additional management with dressing containing nanocrystalline silver and NPWT.
摘要：
背景：慢性伤口易于被革兰氏阳性和革兰氏阴性细菌定植，这些细菌可能对抗菌敷料和全身性抗生素具有抗性。2004年1月，美国食品和药物管理局批准将药用幼虫用于人类和动物的抗性生物。尽管在成人中使用，缺乏评估其在儿科人群中疗效和安全性的证据.
方法：T是一个5岁男孩，有几个慢性伤口感染多重耐药铜绿假单胞菌。伤口最初是用化学清创术治疗的，含有离子银的敷料，负压伤口治疗（NPWT），抗生素没有成功。因此,一个多学科小组实施了the清创疗法（MDT）。
结论：MDT后，一个伤口完全上皮化，其他伤口缩小了70%的上皮化。治疗还减少了伤口的气味，渗出物,和痛苦。在用含有纳米晶银和NPWT的敷料额外处理后,闭合其他伤口。
方法：T是一个5岁男孩，有几个慢性伤口感染多重耐药铜绿假单胞菌。伤口最初是用化学清创术治疗的，含有离子银的敷料，负压伤口治疗（NPWT），抗生素没有成功。因此,一个多学科小组实施了the清创疗法（MDT）。
结论：MDT后，一个伤口完全上皮化，其他伤口缩小了70%的上皮化。治疗还减少了伤口的气味，渗出物,和痛苦。在用含有纳米晶银和NPWT的敷料额外处理后,闭合其他伤口。
