关键词: Anklosing spondylitis COVID-19 Healthcare improvement and patient safety Immunological products and vaccines Vaccination/immunisation

Mesh : Adult Arthritis / etiology COVID-19 / prevention & control Epstein-Barr Virus Infections / complications Female Herpesvirus 4, Human Humans RNA, Messenger SARS-CoV-2 Sacroiliac Joint / diagnostic imaging pathology Sacroiliitis / etiology Vaccination / adverse effects Vaccines, Synthetic mRNA Vaccines

来  源:   DOI:10.1136/bcr-2022-249063   PDF(Pubmed)

Abstract:
A woman in her 30s received a second dose, first booster, Corminaty vaccine against the SARS-CoV-2. Three days later, the patient developed unilateral sacroiliitis. A pelvic scan revealed inflammatory joint edges, bone erosion and a heterogeneous mass of 2.5 cm in the psoas muscle. Joint puncture revealed no microcrystalline deposits, but bone marrow cells, erythroblast were identified. The standard bacterial cultures and culture for mycobacteria were negative. HLA B27 was negative, and no seroconversion was identified for HIV, Epstein-Barr virus, cytomegalovirus, chlamydia or Quantiferon. Two months later, the sacroiliitis resolved.The aetiologic approach of this erosive unilateral acute sacroiliitis in a person naïve to rheumatologic pathology was negative for inflammatory or infectious sacroiliitis. Arthralgias after vaccination are expected. Arthritis is less common, and acute sacroiliitis has not yet been described. Acute sacroiliitis may be considered a reactive sacroiliitis to the anti-COVID-19 mRNA vaccine.
摘要:
一名30多岁的妇女接受了第二剂,第一个助推器,抗SARS-CoV-2的Corminaty疫苗。三天后,患者出现单侧骶髂关节炎.骨盆扫描显示关节边缘发炎,骨侵蚀和腰大肌2.5厘米的异质块。关节穿刺发现没有微晶沉积物,但是骨髓细胞,红细胞被确定。标准细菌培养物和分枝杆菌培养物是阴性的。HLA-B27阴性,没有发现艾滋病毒的血清转化,爱泼斯坦-巴尔病毒,巨细胞病毒,衣原体或Quantiferon。两个月后,骶髂关节炎缓解了.在未接受风湿病学病理的人中,这种糜烂性单侧急性骶髂关节炎的病因对炎症性或感染性骶髂关节炎呈阴性。预计疫苗接种后会出现关节痛。关节炎不太常见,和急性骶髂关节炎尚未被描述。急性骶髂关节炎可被认为是抗COVID-19mRNA疫苗的反应性骶髂关节炎。
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