Abstract：
Pomegranate is a fruit-bearing tree. Pomegranate flowers, leaves, bark, fruit juice, peel and seeds were reported to have pharmacological effects. Recently, the researches about phytochemicals, metabolism and pharmacokinetics studies of different parts of pomegranate were carried out. There is a lack of summary on different parts of pomegranate. Furthermore, we were interested in potential correlations and differences on the phytochemicals, metabolism and pharmacokinetics studies between the different parts of pomegranate. This review is aimed to provide a comprehensive overview of reported researches on different parts of pomegranate about phytochemicals, metabolism and pharmacokinetics studies. Besides, we introduced analysis strategies for identifying phytochemicals in foods/plants and metabolites in biosamples using LC-HR MSn techniques. Furthermore, we firstly speculated structures and the maximum number of constitutional isomers of ellagitannins and gallotannins. This review is helpful for further application to discover more active compounds and their metabolites from pomegranate and other plants/foods.
摘要：
石榴是一种果树。石榴花,叶子,吠叫,果汁,据报道，果皮和种子具有药理作用。最近,关于植物化学物质的研究，对石榴不同部位的代谢和药代动力学进行了研究。对石榴的不同部位缺乏总结。此外，我们对植物化学物质的潜在相关性和差异感兴趣，石榴不同部位之间的代谢和药代动力学研究。本综述旨在对石榴不同部位有关植物化学物质的研究进行全面综述。代谢和药代动力学研究。此外,我们介绍了使用LC-HRMSn技术鉴定食品/植物中的植物化学物质和生物样品中的代谢物的分析策略。此外，我们首先推测了单宁和单宁的结构和组成异构体的最大数量。这篇综述有助于进一步应用于从石榴和其他植物/食品中发现更多的活性化合物及其代谢产物。
