Abstract：
Bipolar disorder is a lifelong condition. Today, there is a urgent need to find indicators of the disease. Specifically, they could be useful to improve the diagnosis and the early detection, the prognosis, to estimate the treatment response and to create homogeneous subgroups of patients based on similar pathophysiological mechanisms. Here, we assume that visual electrophysiology in combination with a neuropsychological assessment can give additional data to routine practice, especially to precise specific damages and pathophysiological characteristics of these patients. Visual electrophysiology is characterized by an electroretinogram and the delivery of visual evoked potentials, which measure retinal and visual cortical neuronal functioning in response to visual stimulations. This review highlights the interest of visual electrophysiology and neuropsychology performed in isolation and to present the benefits of combining these measures. We will review the results based on these measures in patients with bipolar disorders. Finally, we argue for the use of innovative techniques such as signal processing and artificial intelligence techniques for routine care and precision medicine in bipolar disorders.
摘要：
双相情感障碍是一种终身疾病。今天,迫切需要找到这种疾病的指标。具体来说,它们可能有助于改善诊断和早期检测，预后,评估治疗反应，并根据相似的病理生理机制创建同质的患者亚组。这里,我们假设视觉电生理学与神经心理学评估相结合可以为常规实践提供额外的数据，特别是这些患者的具体损害和病理生理特征。视觉电生理学的特征是视网膜电图和视觉诱发电位的传递，测量视网膜和视觉皮层神经元对视觉刺激的反应。这篇综述强调了孤立进行的视觉电生理学和神经心理学的兴趣，并提出了结合这些措施的好处。我们将根据这些措施对双相情感障碍患者进行评估。最后,我们主张将信号处理和人工智能技术等创新技术用于双相情感障碍的常规护理和精准医疗。
