Abstract：
BACKGROUND: To report a late onset, deep stromal and endothelial corneal scar in a keratoconus patient after corneal collagen cross-linking (CXL).
METHODS: Observational case report. A 29-year-old man with bilateral keratoconus received an accelerated (A-CXL 10*9) epithelium-off CXL procedure in the left eye.6-months postoperatively, a 2.2 × 1.2 mm inferocentral corneal scar was detected, which was located in the posterior stroma ranging from approximately 350 µm until the endothelium, therefore was situated below the demarcation line. A topical corticosteroid treatment did not influence the magnitude or configuration of the scar. Visual acuity was never affected, which includes the examination 12 months postoperatively.
CONCLUSIONS: We report a case of a late onset deep stromal and endothelial corneal scar 6 months after accelerated CXL as postoperative complication without affecting visual acuity.
METHODS: Observational case report. A 29-year-old man with bilateral keratoconus received an accelerated (A-CXL 10*9) epithelium-off CXL procedure in the left eye.6-months postoperatively, a 2.2 × 1.2 mm inferocentral corneal scar was detected, which was located in the posterior stroma ranging from approximately 350 µm until the endothelium, therefore was situated below the demarcation line. A topical corticosteroid treatment did not influence the magnitude or configuration of the scar. Visual acuity was never affected, which includes the examination 12 months postoperatively.
CONCLUSIONS: We report a case of a late onset deep stromal and endothelial corneal scar 6 months after accelerated CXL as postoperative complication without affecting visual acuity.
摘要：
背景：报告晚发病，角膜胶原交联（CXL）后圆锥角膜患者的深层基质和内皮角膜瘢痕。
方法：观察性病例报告。一名29岁的双侧圆锥角膜患者接受了左眼加速（A-CXL10*9）上皮外CXL手术。术后6个月，检测到2.2×1.2毫米的角膜中央下瘢痕，它位于大约350微米的后基质中，直到内皮，因此位于分界线以下。局部皮质类固醇治疗不会影响瘢痕的大小或构型。视力从未受到影响，其中包括术后12个月的检查。
结论：我们报告了一例在CXL加速后6个月出现迟发性深基质和内皮角膜瘢痕的情况，这是术后并发症，但不影响视力。
方法：观察性病例报告。一名29岁的双侧圆锥角膜患者接受了左眼加速（A-CXL10*9）上皮外CXL手术。术后6个月，检测到2.2×1.2毫米的角膜中央下瘢痕，它位于大约350微米的后基质中，直到内皮，因此位于分界线以下。局部皮质类固醇治疗不会影响瘢痕的大小或构型。视力从未受到影响，其中包括术后12个月的检查。
结论：我们报告了一例在CXL加速后6个月出现迟发性深基质和内皮角膜瘢痕的情况，这是术后并发症，但不影响视力。
