PDF(Pubmed)
Abstract：
OBJECTIVE: To determine incidence trends of Staphylococcus aureus bacteremia (SAB) from population-based studies from multiple countries.
METHODS: A contemporary systematic review was conducted using Ovid Cochrane Central Register of Controlled Trials (1991+), Ovid Embase (1974+), Ovid Medical Literature Analysis and Retrieval System Online (MEDLINE) (1946+ including epub ahead of print, in-process & other non-indexed citations), and Web of Science Core Collection (Science Citation Index Expanded 1975+ and Emerging Sources Citation Index 2015+). Two authors (J.R.H. and J.A.Q.M.) independently reviewed all studies and included those that reported population-based incidence of SAB in patients aged 18 years and older.
RESULTS: Twenty-six studies met inclusion criteria with the highest number (n=6) of studies conducted in Canada. The incidence of SAB ranged from 9.3 to 65 cases/100,000/year. The median age of patients with SAB ranged from 62 to 72 years and SAB cases were more commonly observed in men than in women. The most common infection sources were intravascular catheters and skin and soft tissue infections. SAB incidence trends demonstrated high variability for geographic regions and calendar years. Overall, there was no change in the incidence trend across all studies during the past two decades.
CONCLUSIONS: Multiple factors, both pros, and cons are likely responsible for the overall stable SAB incidence in countries included in this systematic review. Some of these factors vary in geographic location and prompt additional investigations from countries not included in the current review so that a more global characterization is defined.
METHODS: A contemporary systematic review was conducted using Ovid Cochrane Central Register of Controlled Trials (1991+), Ovid Embase (1974+), Ovid Medical Literature Analysis and Retrieval System Online (MEDLINE) (1946+ including epub ahead of print, in-process & other non-indexed citations), and Web of Science Core Collection (Science Citation Index Expanded 1975+ and Emerging Sources Citation Index 2015+). Two authors (J.R.H. and J.A.Q.M.) independently reviewed all studies and included those that reported population-based incidence of SAB in patients aged 18 years and older.
RESULTS: Twenty-six studies met inclusion criteria with the highest number (n=6) of studies conducted in Canada. The incidence of SAB ranged from 9.3 to 65 cases/100,000/year. The median age of patients with SAB ranged from 62 to 72 years and SAB cases were more commonly observed in men than in women. The most common infection sources were intravascular catheters and skin and soft tissue infections. SAB incidence trends demonstrated high variability for geographic regions and calendar years. Overall, there was no change in the incidence trend across all studies during the past two decades.
CONCLUSIONS: Multiple factors, both pros, and cons are likely responsible for the overall stable SAB incidence in countries included in this systematic review. Some of these factors vary in geographic location and prompt additional investigations from countries not included in the current review so that a more global characterization is defined.
摘要：
目的：从多个国家的人群研究中确定金黄色葡萄球菌菌血症（SAB）的发病趋势。
方法：使用OvidCochrane中央对照试验注册（1991年）进行了当代系统综述，OvidEmbase(1974+)Ovid在线医学文献分析和检索系统（MEDLINE）（1946+包括epub，过程中和其他非索引引文)，和WebofScience核心收藏（科学引文索引扩展1975+和新兴来源引文索引2015+）。两位作者(J.R.H.和J.A.Q.M.）独立审查了所有研究，并包括那些报告18岁及以上患者中基于人群的SAB发生率的研究。
结果：26项研究符合纳入标准，在加拿大进行的研究数量最多（n=6）。SAB的发病率范围为9.3至65例/100,000/年。SAB患者的中位年龄为62至72岁，男性比女性更常见。最常见的感染源是血管内导管和皮肤软组织感染。SAB的发病率趋势显示出地理区域和日历年的高变异性。总的来说,在过去的20年中,所有研究的发病率趋势没有变化.
结论：多重因素，两位专业人士,在本系统评价中纳入的国家中,SAB发病率总体稳定的原因可能是利弊.其中一些因素因地理位置而异，并促使来自当前审查中未包括的国家的更多调查，以便界定更全面的特征。
方法：使用OvidCochrane中央对照试验注册（1991年）进行了当代系统综述，OvidEmbase(1974+)Ovid在线医学文献分析和检索系统（MEDLINE）（1946+包括epub，过程中和其他非索引引文)，和WebofScience核心收藏（科学引文索引扩展1975+和新兴来源引文索引2015+）。两位作者(J.R.H.和J.A.Q.M.）独立审查了所有研究，并包括那些报告18岁及以上患者中基于人群的SAB发生率的研究。
结果：26项研究符合纳入标准，在加拿大进行的研究数量最多（n=6）。SAB的发病率范围为9.3至65例/100,000/年。SAB患者的中位年龄为62至72岁，男性比女性更常见。最常见的感染源是血管内导管和皮肤软组织感染。SAB的发病率趋势显示出地理区域和日历年的高变异性。总的来说,在过去的20年中,所有研究的发病率趋势没有变化.
结论：多重因素，两位专业人士,在本系统评价中纳入的国家中,SAB发病率总体稳定的原因可能是利弊.其中一些因素因地理位置而异，并促使来自当前审查中未包括的国家的更多调查，以便界定更全面的特征。
