Abstract:
Biliary duct hamartomas are benign intrahepatic bile duct lesions. Despite being primarily incidental findings on imaging, these lesions can provide a diagnostic conundrum due to their shared characteristics with malignant tumors. The goal of this systematic review is to offer a thorough clinical profile of biliary duct hamartomas. There were 139 cases of biliary duct hamartomas identified in a structured systematic review of the literature. Patient demographics, clinical presentation, significant laboratory and imaging data, diagnostic modalities, treatment choices, and outcomes were all studied and reported. Biliary duct hamartomas present with mild symptoms and laboratory abnormalities, and while being visible on imaging, the results are non-specific and may require biopsy in case of red flag signs such as weight loss and a progressive increase in the size of the lesion. Furthermore, there are currently no published guidelines for the treatment of biliary duct hamartomas, and many people have had surgery despite the clinically benign nature of these abnormalities. As per the findings of the study, individuals who exhibit signs of malignancy should be investigated further. Eyeballing for red flag symptoms, followed by a specialized imaging scan and invasive treatment, is the three-step approach to biliary duct hamartomas. Since our recommendations include a shift in strategy and do not contradict existing rules, there are likely to be few roadblocks to improvement; the key barriers being technological equipment and image quality. In this study, we intended to pave the way for future research in the field. In our opinion, the next decade will bring a better understanding of the characteristics of biliary hamartomas, disease symptoms, and better recognition of any suspicious features. These indications will aid in reducing the number of unneeded surgical or invasive operations. Finally, the findings of these future studies will allow the medical community to improve and provide the best care possible.
摘要:
胆管错构瘤是良性肝内胆管病变。尽管主要是影像学上的偶然发现,由于这些病变与恶性肿瘤的共同特征,它们可以提供诊断难题。这项系统评价的目的是提供胆管错构瘤的全面临床资料。在结构化的系统文献回顾中,发现了139例胆管错构瘤。患者人口统计学,临床表现,重要的实验室和成像数据,诊断方式,治疗选择,和结局都进行了研究和报告.胆管错构瘤表现为轻度症状和实验室异常,在成像时可见的同时,结果是非特异性的,如果出现危险信号,如体重减轻和病变大小逐渐增加,可能需要进行活检。此外,目前尚无关于胆管错构瘤的治疗指南,尽管这些异常在临床上是良性的,但许多人还是接受了手术。根据研究结果,表现出恶性肿瘤迹象的个体应进一步调查.因危险信号症状而出现眼睛跳动,然后进行专门的成像扫描和侵入性治疗,是胆管错构瘤的三步法。由于我们的建议包括战略的转变,并且不违反现有规则,改进的障碍可能很少;关键障碍是技术设备和图像质量。在这项研究中,我们打算为该领域的未来研究铺平道路。在我们看来,未来十年将使人们更好地了解胆道错构瘤的特征,疾病症状,更好地识别任何可疑特征。这些适应症将有助于减少不必要的外科手术或侵入性手术的数量。最后,这些未来研究的结果将使医学界能够改善并提供尽可能好的护理。