PDF(Pubmed)
Abstract：
UNASSIGNED: To report a case series of lacrimal duct obstruction and infection associated with non-traumatic corneal perforation.
UNASSIGNED: This study included 6 eyes in 6 patients with non-traumatic corneal perforation treated between April 2019 and March 2021. All 6 cases were associated with lacrimal duct obstruction and infection. Purulent discharge caused by lacrimal duct infection was observed in all 6 patients (100%). However, three of the 6 patients (50%) did not show purulent discharge at initial examination and lacrimal duct obstruction was therefore not initially recognized. Dry eye was observed in five of the 6 patients (83%) and may have caused corneal deterioration, increasing susceptibility to perforation. Further, dry eye masks symptoms of lacrimal duct obstruction and infections, such as epiphora and regurgitation of purulent discharge, making the association with lacrimal duct obstruction and infection difficult to determine. All patients were treated for both corneal perforation and lacrimal duct disease, and conditions improved, with no recurrence of either corneal perforation or lacrimal duct disease.
UNASSIGNED: In patients with a combination of lacrimal duct disease and corneal perforation, treatment of both diseases resulted in stabilization of patient condition. Dry eyes may mask symptoms of lacrimal duct diseases, such as epiphora and purulent discharge, and lacrimal duct disease may thus be underdiagnosed.
UNASSIGNED: This study included 6 eyes in 6 patients with non-traumatic corneal perforation treated between April 2019 and March 2021. All 6 cases were associated with lacrimal duct obstruction and infection. Purulent discharge caused by lacrimal duct infection was observed in all 6 patients (100%). However, three of the 6 patients (50%) did not show purulent discharge at initial examination and lacrimal duct obstruction was therefore not initially recognized. Dry eye was observed in five of the 6 patients (83%) and may have caused corneal deterioration, increasing susceptibility to perforation. Further, dry eye masks symptoms of lacrimal duct obstruction and infections, such as epiphora and regurgitation of purulent discharge, making the association with lacrimal duct obstruction and infection difficult to determine. All patients were treated for both corneal perforation and lacrimal duct disease, and conditions improved, with no recurrence of either corneal perforation or lacrimal duct disease.
UNASSIGNED: In patients with a combination of lacrimal duct disease and corneal perforation, treatment of both diseases resulted in stabilization of patient condition. Dry eyes may mask symptoms of lacrimal duct diseases, such as epiphora and purulent discharge, and lacrimal duct disease may thus be underdiagnosed.
摘要：
■报告一系列与非创伤性角膜穿孔相关的泪道阻塞和感染病例。
■这项研究包括2019年4月至2021年3月期间治疗的6例非创伤性角膜穿孔患者的6只眼。6例均伴有泪道阻塞和感染。在所有6例患者中均观察到由泪道感染引起的化脓性分泌物（100％）。然而,6例患者中有3例(50%)在初次检查时未出现脓性分泌物,因此最初未发现泪道阻塞.在6例患者中有5例（83％）观察到干眼，可能导致角膜恶化，增加穿孔的敏感性。Further,干眼症的症状，泪道阻塞和感染，如溢泪和脓性分泌物的反流，使得与泪道阻塞和感染的关联难以确定。所有患者均接受角膜穿孔和泪道疾病治疗，条件改善了,无角膜穿孔或泪道疾病复发。
■患有泪道疾病和角膜穿孔的患者，两种疾病的治疗导致患者病情稳定。干眼可能掩盖泪道疾病的症状，如泪液和脓性分泌物，因此，泪道疾病可能被低估。
■这项研究包括2019年4月至2021年3月期间治疗的6例非创伤性角膜穿孔患者的6只眼。6例均伴有泪道阻塞和感染。在所有6例患者中均观察到由泪道感染引起的化脓性分泌物（100％）。然而,6例患者中有3例(50%)在初次检查时未出现脓性分泌物,因此最初未发现泪道阻塞.在6例患者中有5例（83％）观察到干眼，可能导致角膜恶化，增加穿孔的敏感性。Further,干眼症的症状，泪道阻塞和感染，如溢泪和脓性分泌物的反流，使得与泪道阻塞和感染的关联难以确定。所有患者均接受角膜穿孔和泪道疾病治疗，条件改善了,无角膜穿孔或泪道疾病复发。
■患有泪道疾病和角膜穿孔的患者，两种疾病的治疗导致患者病情稳定。干眼可能掩盖泪道疾病的症状，如泪液和脓性分泌物，因此，泪道疾病可能被低估。
