Abstract：
The coexistence of multiple autoantibodies associated with autoimmune encephalitis (AE) is rare. A 63-year-old woman developed psychosis and consciousness disorder. Her cerebrospinal fluid was positive for anti-N-methyl-D-aspartate receptor antibodies, and her serum was positive for anti-Hu antibodies. Enhanced computed tomography revealed a mass in the right pulmonary hilum. AE complicated with small-cell lung cancer was diagnosed. Immunotherapy (steroid therapy and intravenous immunoglobulin) and four courses of carboplatin-etoposide chemotherapy were required to improve her neurological symptoms. When the coexistence of multiple antibodies is detected, despite its rarity, aggressive detection and treatment of any underlying malignancy may be recommended.
摘要：
与自身免疫性脑炎（AE）相关的多种自身抗体共存很少。一名63岁的妇女患有精神病和意识障碍。她的脑脊液抗N-甲基-D-天冬氨酸受体抗体阳性，血清抗Hu抗体呈阳性.增强计算机断层扫描显示右肺门有肿块。诊断为AE并发小细胞肺癌。需要免疫治疗（类固醇治疗和静脉注射免疫球蛋白）和四个疗程的卡铂-依托泊苷化疗来改善她的神经系统症状。当检测到多种抗体共存时，尽管它很罕见,建议积极检测和治疗任何潜在的恶性肿瘤.
