关键词: Anterior chamber Ophthalmology

Mesh : Actinobacteria Anti-Bacterial Agents / therapeutic use Humans Keratitis, Herpetic / diagnosis drug therapy Male Neoplasm Recurrence, Local

来  源:   DOI:10.1136/bcr-2022-248988   PDF(Pubmed)

Abstract:
A man in his 20s, with irritation, pain and photophobia in the left eye, was clinically diagnosed with herpes simplex virus nummular keratitis at our institute and advised topical antivirals and corticosteroids, causing resolution of active infiltrates. The infection recurred after 7 months and the patient did not respond to the previous regimen, so corneal scraping was sent for microbiological evaluation. Gram-positive bacilli grew on culture, which were identified as Atopobium vaginae using VITEK 2 Compact system (bioMérieux, Marcy l\'Etoile, France). Gatifloxacin eye drops were added based on antibiotic sensitivity patterns. Infiltrates resolved completely, leaving behind residual scars without any recurrences. This is the first reported case of corneal infection caused by A. vaginae, a bacterium known to reside in the urogenital tract. It caused secondary corneal infection in a case of recurrent herpes simplex keratitis. Species identification systems like VITEK 2 Compact can help identify such rare bacteria with great accuracy.
摘要:
一个20多岁的男人,带有刺激,左眼疼痛和畏光,在我们研究所临床诊断为单纯疱疹病毒性角膜炎,并建议局部使用抗病毒药物和皮质类固醇,导致主动渗透的解决。7个月后感染复发,患者对以前的方案没有反应,所以角膜刮片被送去进行微生物评估。革兰氏阳性杆菌在培养物中生长,使用VITEK2Compact系统(bioMérieux,Marcyl\'Etoile,法国)。根据抗生素敏感性模式添加加替沙星滴眼液。渗透完全解决,留下残留的疤痕没有任何复发。这是第一例报道的由A.vaginae引起的角膜感染病例,一种已知存在于泌尿生殖道的细菌。在复发性单纯疱疹性角膜炎的情况下,它引起继发性角膜感染。像VITEK2Compact这样的物种识别系统可以帮助非常准确地识别这种稀有细菌。
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