关键词: Antimicrobial stewardship Feedback Guideline compliance Surgery Surgical antibiotic prophylaxis Time series

Mesh : Humans Anti-Bacterial Agents / therapeutic use Antibiotic Prophylaxis / methods Retrospective Studies Prospective Studies Feedback Interrupted Time Series Analysis Guideline Adherence Surgical Wound Infection / prevention & control drug therapy

来  源:   DOI:10.1016/j.ajic.2022.06.015

Abstract:
Surgical antibiotic prophylaxis (SAP) has been proved to decrease the rate of surgical site infections (SSI), but compliance to SAP guidelines remains suboptimal.
This study evaluated the impact of periodically sending individualized feedback letters to surgeons and anesthesiologists on their compliance rate to SAP guidelines.
A total of 1491 surgeries were evaluated by retrospective chart review during the pre-intervention period and 668 surgeries were evaluated by prospective chart review during the per-intervention period. Finally, 295 letters were sent to 64 surgeons and 45 anesthesiologists. Compliance rate was assessed as an outcome composed of: indication for SAP, choice of antibiotic agent, antibiotic dose, postoperative duration, timing of the preoperative dose and intraoperative redosing. An interrupted time series design was used to assess a difference on compliance rates before and during the intervention period.
Sending individualized feedback letters to surgeons and anesthesiologists did not significantly improve the overall compliance to local SAP guidelines.
Individualized feedback letters could be part of future interventions directed at improving compliance to SAP guidelines, but are likely insufficient by themselves to provide significant results.
摘要:
背景:手术抗生素预防(SAP)已被证明可以降低手术部位感染(SSI)的发生率,但对SAP指南的遵从性仍然欠佳。
目的:本研究评估了定期向外科医生和麻醉师发送个性化反馈信对他们对SAP指南的依从率的影响。
方法:在干预前期间,对1491例手术进行了回顾性评估,在每个干预期间,对668例手术进行了前瞻性评估。最后,向64位外科医生和45位麻醉师发送了295封信。合规率被评估为一个结果,包括:SAP的适应症,抗生素的选择,抗生素剂量,术后持续时间,术前剂量和术中再给药的时机。中断的时间序列设计用于评估干预前和干预期间的依从率差异。
结果:向外科医生和麻醉师发送个性化反馈信并没有显著提高对当地SAP指南的总体依从性。
结论:个性化反馈信可能是未来干预措施的一部分,旨在提高SAP指南的合规性。但本身可能不足以提供显著的结果。
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