Abstract：
Enterococcus spp. are Gram-positive, heterogeneous lactic acid bacteria inhabiting various environments. Several species of Enterococci are considered to be able to stimulate the immune system and play an important role in intestinal homeostasis. Some Enterococci can be used as probiotics. Some strains of E. faecium are components of pharmaceutical products used to treat diarrhea, antibiotic-associated diarrhea, or irritable bowel syndrome (IBS). However, it has been proved that they are responsible for food contamination, and are sometimes undesirable from the point of view of food technology. Additionally, the virulence and multi-drug resistance of Enterococci potentially pose a risk of an epidemic, especially in hospital environments. Moreover, there are indications of their negative role in colon tumorigenesis; however, some nterococci are proved to support immunotherapy in cancer treatment. In general, it can be concluded that this group of microorganisms, despite its nature, has properties that can be used to support cancer treatment-both aggressive chemotherapy and cutting-edge therapy targeting immune checkpoints (IC).
摘要：
肠球菌属。是革兰氏阳性，居住在各种环境中的异质乳酸菌。几种肠球菌被认为能够刺激免疫系统并在肠稳态中起重要作用。一些肠球菌可用作益生菌。一些屎肠球菌菌株是用于治疗腹泻的药物产品的成分，抗生素相关性腹泻,或肠易激综合征（IBS）。然而,事实证明，它们是造成食品污染的原因，从食品技术的角度来看，有时是不受欢迎的。此外,肠球菌的毒力和多重耐药性可能构成流行的风险，尤其是在医院环境中。此外，有迹象表明它们在结肠肿瘤发生中的负面作用；然而，一些肠球菌被证明在癌症治疗中支持免疫疗法。总的来说,可以得出结论，这组微生物，尽管它的性质,具有可用于支持癌症治疗的特性-积极的化学疗法和针对免疫检查点（IC）的尖端疗法。
