关键词: RCVS hemorrhagic postpartum

来  源:   DOI:10.3390/neurolint14020040

Abstract:
(1) Background: Reversible cerebral vasoconstriction syndrome (RCVS) encompasses a clinical and radiological diagnosis characterized by recurrent thunderclap headache, with or without focal deficits due to multifocal arterial vasoconstriction and dilation. RCVS can be correlated to pregnancy and exposure to certain drugs. Currently, the data on prevalence of RCVS in the postpartum period is lacking. We aim to investigate the prevalence of RCVS in the postpartum period and the rate of hemorrhagic complications of RCVS among the same group of patients; (2) Methods: We conducted the metanalysis by using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), and Meta-Analyses and Systematic Reviews of Observational Studies in Epidemiology (MOOSE) protocol. To analyze the Bias, we used the Ottawa Newcastle scale tool. We included only full-text observational studies conducted on humans and written in English. We excluded Literature Reviews, Systematic Reviews, and Metanalysis. Additionally, we excluded articles that did not document the prevalence of RCVS in the postpartum period (3). Results: According to our analysis, the Prevalence of RCVS in the postpartum period was 129/1083 (11.9%). Of these, 51/100 (52.7%) patients had hemorrhagic RCVS vs. 49/101 (49.5%) with non-hemorrhagic RCVS. The rates of Intracerebral Hemorrhage (ICH) and Subarachnoid Hemorrhage (SAH) were (51.6% and 10.7%, respectively. ICH seems to be more common than.; (4) Conclusions: Among patients with RCVS, the prevalence in PP patients is relativity high. Pregnant women with RCVS have a higher recurrence of hemorrhagic vs. non-hemorrhagic RCVS. Regarding the type of Hemorrhagic RCVS, ICH is more common than SAH among patients in the postpartum period. Female Sex, history of migraine, and older age group (above 45) seem to be risk factors for H-RCVS. Furthermore, recurrence of RCVS is associated with a higher age group (above 45). Recurrence of RCVS is more commonly idiopathic than being triggered by vasoactive drugs in the postpartum period.
摘要:
(1)背景:可逆性脑血管收缩综合征(RCVS)包括临床和放射学诊断,其特征是复发性雷击头痛,有或没有由于多灶性动脉血管收缩和扩张引起的局灶性缺陷。RCVS可能与怀孕和暴露于某些药物有关。目前,缺乏产后RCVS患病率的数据.我们旨在调查同一组患者中产后RCVS的患病率和RCVS出血性并发症的发生率;(2)方法:我们使用系统评价和荟萃分析(PRISMA)的首选报告项目进行meta分析,流行病学观察性研究(MOOSE)方案的Meta分析和系统评价。为了分析偏见,我们使用了渥太华纽卡斯尔秤工具。我们仅包括对人类进行的全文观察研究,并以英语撰写。我们排除了文学评论,系统审查,和Metanalysis。此外,我们排除了未记录产后RCVS患病率的文章(3).结果:根据我们的分析,产后RCVS的患病率为129/1083(11.9%).其中,51/100(52.7%)患者出血性RCVS与49/101(49.5%)伴有非出血性RCVS。脑出血(ICH)和蛛网膜下腔出血(SAH)的发生率分别为(51.6%和10.7%,分别。ICH似乎比更常见。(4)结论:在RCVS患者中,PP患者的患病率相对较高。患有RCVS的孕妇出血性复发率较高。非出血性RCVS.关于出血性RCVS的类型,在产后患者中,ICH比SAH更常见。女性性别,偏头痛史,年龄较大的人群(45岁以上)似乎是H-RCVS的危险因素。此外,RCVS的复发与较高年龄组(45岁以上)相关.RCVS的复发通常是特发性的,而不是在产后由血管活性药物触发。
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