关键词: angiotensin-converting enzyme 2 receptor (ACE-2) chemical senses novel coronavirus disease (COVID-19) olfactory dysfunction taste dysfunction

Mesh : COVID-19 / epidemiology Humans Prevalence SARS-CoV-2 Taste Disorders

来  源:   DOI:10.3389/fpubh.2022.839182   PDF(Pubmed)

Abstract:
Emerging viral infections are a ceaseless challenge and remain a global public health concern. The world has not yet come back to normal from the devastating effects of the highly contagious and pathogenic novel coronavirus, or Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Olfactory and taste dysfunction is common in patients infected by the novel coronavirus. In light of the emergence of different coronavirus variants, it is important to update the prevalence and pathophysiology of these side effects. In this review, articles published on the prevalence of olfactory and taste dysfunction from coronavirus disease (COVID-19) and their possible pathophysiologic mechanisms have been reviewed and reported. The modulatory role of different SARS-CoV-2 variants on the chemical senses is then described. The clinical relevance of chemical sense disorder and its long-term morbidity and management is also discussed.
摘要:
新出现的病毒感染是一个不断的挑战,仍然是全球公共卫生问题。世界尚未从高度传染性和致病性新型冠状病毒的破坏性影响中恢复正常,或严重急性呼吸系统综合症冠状病毒2(SARS-CoV-2)。嗅觉和味觉功能障碍在感染新型冠状病毒的患者中很常见。鉴于不同冠状病毒变体的出现,重要的是更新这些副作用的患病率和病理生理学。在这次审查中,发表了关于冠状病毒病(COVID-19)引起的嗅觉和味觉功能障碍的患病率及其可能的病理生理机制的文章。然后描述了不同SARS-CoV-2变体对化学意义的调节作用。还讨论了化学意义障碍的临床相关性及其长期发病率和管理。
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