在患有 DICER1 综合征和 NRAS 突变型神经皮肤黑变病的儿童中 , DICER1 突变型中枢神经系统肉瘤的神经 c 细胞起源的证据。
关键词: DICER1 mutant CNS sarcoma DNA methylation profiling NRAS neural crest cell neurocutaneous melanosis pseudo-meissnerian corpuscle DICER1 mutant CNS sarcoma DNA methylation profiling NRAS neural crest cell neurocutaneous melanosis pseudo-meissnerian corpuscle
Mesh : Child DEAD-box RNA Helicases GTP Phosphohydrolases Humans Magnetic Resonance Imaging Melanosis / genetics Membrane Proteins Neural Crest Neurocutaneous Syndromes / genetics Ribonuclease III / genetics Sarcoma Child DEAD-box RNA Helicases GTP Phosphohydrolases Humans Magnetic Resonance Imaging Melanosis / genetics Membrane Proteins Neural Crest Neurocutaneous Syndromes / genetics Ribonuclease III / genetics Sarcoma